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MAB4337

Sigma-Aldrich

Anti-UTF-1 Antibody, clone 5G10.2

clone 5G10.2, Chemicon®, from mouse

Synonym(s):

Anti-AI505934

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

5G10.2, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

input

sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)
sample type: human embryonic stem cell(s)

isotype

IgG1κ

NCBI accession no.

NM_003577.2

UniProt accession no.

Q5T230

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... UTF1(8433)

General description

UTF1 is a transcription factor that was originally identified due to its expression in Embryonic Stem (ES) cells, Embryonic Carcinoma (EC) cells, and germ line tissues. Expression was not found in adult tissues. It was thought at the time that UTF1 might play an important role in early molecular events of embryogenesis. Subsequent studies have shown that UTF1 is a target of the Oct-4 / Sox-2 complex, a key determinant of pluripotency in stem cells

Immunogen

Recombinant GST Fusion protein, human UTF-1

Application

Anti-UTF-1 Antibody, clone 5G10.2 detects level of UTF-1 & has been published & validated for use in ELISA, WB & IC.

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hanna Valli et al.
Fertility and sterility, 102(2), 566-580 (2014-06-04)
To determine the molecular characteristics of human spermatogonia and optimize methods to enrich spermatogonial stem cells (SSCs). Laboratory study using human tissues. Research institute. Healthy adult human testicular tissue. Human testicular tissue was fixed or digested with enzymes to produce
A L Caldeira-Brant et al.
Reproduction (Cambridge, England), 159(4), 437-451 (2020-01-29)
Human spermatogonial stem cells (SSCs) are an essential source to maintain spermatogenesis as an efficient process for daily sperm production with high self-renewal capacity along adulthood. However, the phenotype and the subpopulation that represent the real reserve SSC for the
Xiao-Ling Wu et al.
Carcinogenesis, 34(7), 1660-1668 (2013-03-29)
Undifferentiated embryonic cell transcription factor-1 (UTF1) is an important transcription factor during development, which plays critical roles in cell fate determination. However, its expression and function in somatic tissues remain unclear. Here, we investigated the expression pattern of the UTF1
Sabine Conrad et al.
Stem cells international, 2016, 8582526-8582526 (2015-12-10)
The aim of this study was to elucidate the molecular status of single human adult germ stem cells (haGSCs) and haGSC colonies, which spontaneously developed from the CD49f MACS and matrix- (collagen-/laminin+ binding-) selected fraction of enriched spermatogonia. Single-cell transcriptional
H Valli-Pulaski et al.
Human reproduction (Oxford, England), 34(6), 966-977 (2019-05-22)
Is it feasible to disseminate testicular tissue cryopreservation with a standardized protocol through a coordinated network of centers and provide centralized processing/freezing for centers that do not have those capabilities? Centralized processing and freezing of testicular tissue from multiple sites
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