Skip to Content
Merck
All Photos(4)

Key Documents

S2201

Sigma-Aldrich

Semicarbazide hydrochloride

≥99%

Synonym(s):

N-Aminourea hydrochloride, Hydrazine carboxamide hydrochloride

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
NH2CONHNH2 · HCl
CAS Number:
Molecular Weight:
111.53
Beilstein:
3593642
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥99%

mp

175-177 °C (dec.) (lit.)

SMILES string

Cl.NNC(N)=O

InChI

1S/CH5N3O.ClH/c2-1(5)4-3;/h3H2,(H3,2,4,5);1H

InChI key

XHQYBDSXTDXSHY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Derivatization reagent for aldehydes and ketones which produces crystalline compounds with characteristic melting points.
Semicarbazide hydrochloride is a general reagent used to synthesize semicarbazones from aldehydes and ketones. It can be used to build a variety of heterocyclic compounds, some of which are potent antimicrobial and antiviral agents. It can also be used to prepare corrosion inhibitors.

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 Oral

Target Organs

Bone

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and antimalarial activity of semicarbazone and thiosemicarbazone derivatives.
de Oliveira R B, et al.
European Journal of Medicinal Chemistry, 43(9), 1983-1988 (2008)
Synthesis of some new azole, azepine, pyridine, and pyrimidine derivatives using 6?hydroxy?4H?4?oxo [1]?benzopyran?3?carboxaldehyde as a versatile starting material.
Abdel?Rahman A H, et al.
Heteroatom Chem., 16(1), 20-27 (2005)
Synthesis and antimicrobial activity of some novel derivatives of benzofuran: Part 2. The synthesis and antimicrobial activity of some novel 1-(1-benzofuran-2-yl)-2-mesitylethanone derivatives.
Kirilmis C, et al.
European Journal of Medicinal Chemistry, 43(2), 300-308 (2008)
Design, synthesis, and biological evaluation of antiviral agents targeting flavivirus envelope proteins.
Li Z, et al.
Journal of Medicinal Chemistry, 51(15), 4660-4671 (2008)
Semicarbazide.
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service