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P19809

Sigma-Aldrich

2-Phenylbenzimidazole

97%

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About This Item

Empirical Formula (Hill Notation):
C13H10N2
CAS Number:
716-79-0
Molecular Weight:
194.23
EC Number:
211-939-2
MDL number:
MFCD00005592
UNSPSC Code:
12352100
eCl@ss:
32151902
PubChem Substance ID:
24898258
NACRES:
NA.22

Quality Level

100

Assay

97%

form

solid

mp

293-296 °C (lit.)

SMILES string

c1ccc(cc1)-c2nc3ccccc3[nH]2

InChI

1S/C13H10N2/c1-2-6-10(7-3-1)13-14-11-8-4-5-9-12(11)15-13/h1-9H,(H,14,15)

InChI key

DWYHDSLIWMUSOO-UHFFFAOYSA-N

Gene Information

human ... FGFR1(2260) , PDGFRB(5159)

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Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H315,H318,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yukio Kubota et al.
Nucleic acids research. Supplement (2001), (2)(2), 193-194 (2003-08-09)
We have studied the influence of terminal substituents, amidinium group and N-methylpiperazine ring, of 2-phenylbenzimidazole compounds (1-6; Figure 1) on their DNA-binding modes. Experimental results reveal that 1-3 are accepted in intercalation pockets owing to structural flexibility of the N-methylpiperazine
Michele Tonelli et al.
Bioorganic & medicinal chemistry, 18(6), 2304-2316 (2010-03-02)
Starting from a series of our new 2-phenylbenzimidazole derivatives, shown to be selectively and potently active against the bovine viral diarrhea virus (BVDV), we developed a hierarchical combined experimental/molecular modeling strategy to explore the drug leads for the BVDV RNA-dependent
Mehrorang Ghaedi et al.
Journal of hazardous materials, 158(1), 131-136 (2008-03-04)
A new and efficient solid phase extraction method is described for the preconcentration of trace heavy metal ions. The method is based on the adsorption of Fe(3+), Cu(2+) and Zn(2+) on 2-phenyl-1H-benzo[d] imidazole (PHBI) loaded on Triton X-100-coated polyvinyl chloride
J Johnson Inbaraj et al.
Photochemistry and photobiology, 75(2), 107-116 (2002-03-09)
The sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid (PBSA) and its parent 2-phenylbenzimidazole (PBI) cause DNA photodamage via both Type-I and Type-II mechanisms when UVB irradiated. We have studied the photophysical and photochemical properties of these compounds and their ability to photogenerate reactive
C Stevenson et al.
Chemical research in toxicology, 12(1), 38-45 (1999-01-20)
Gel sequencing experiments with end-labeled synthetic oligodeoxyribonucleotides have established that 2-phenylbenzimidazole (PBZ) and the common sunscreen constituent 2-phenylbenzimidazole-5-sulfonic acid (PBSA) function as efficient photosensitizers of DNA damage when they are exposed to UV-B (290-320 nm) radiation or natural sunlight. Although
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