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A0542

Sigma-Aldrich

Amprolium hydrochloride

Synonym(s):

1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridinium chloride

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About This Item

Linear Formula:
C14H19N4Cl · HCl
CAS Number:
137-88-2
Molecular Weight:
315.24
Beilstein:
4118699
EC Number:
205-307-5
MDL number:
MFCD00078831
UNSPSC Code:
12161900
PubChem Substance ID:
24890432
NACRES:
NA.25

description

cationic

Assay

≥98.0% (TLC)

form

powder

mol wt

315.24 g/mol

technique(s)

cell culture | mammalian: suitable
microbiological culture: suitable

SMILES string

[Cl-].Cl[H].CCCc1ncc(C[n+]2ccccc2C)c(N)n1

InChI

1S/C14H19N4.2ClH/c1-3-6-13-16-9-12(14(15)17-13)10-18-8-5-4-7-11(18)2;;/h4-5,7-9H,3,6,10H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1

InChI key

PJBQYZZKGNOKNJ-UHFFFAOYSA-M

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Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H317,H334

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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S Squadrone et al.
Journal of pharmaceutical and biomedical analysis, 48(5), 1457-1461 (2008-11-04)
As a consequence of the finding of veterinarian drugs in food European Community banned several compounds like coccidiostats as amprolium (APL). This antibiotic has been used as a preventive and clinical anticoccidial drug in chicken. The 2005/187/CE, 2005/925/EC Recommendations ban
Anakalo Shitandi et al.
Journal of veterinary science, 7(2), 177-180 (2006-04-29)
A Bacillus stearothermophilus var. calidolactis C953 tube test was evaluated for its ability in detecting the residue of selected anticoccidial drugs in poultry, specially sulfamethazine, furazolidone, and amprolium. Various concentrations of each drug were injected into chicken liver and kidney
G Rindi et al.
Metabolic brain disease, 18(4), 245-263 (2004-05-07)
Thiamine (T) analogues pyrithiamine, oxythiamine or amprolium in amounts 10-1000 times higher than labelled T, were i.p. injected into rats together with 14C-T (30 microg; 46.25 KBq). The radioactivity associated with T and its phosphoesters in the plasma and cerebral
Zun-Ji Ke et al.
Alcoholism, clinical and experimental research, 33(6), 1097-1103 (2009-04-23)
Heavy alcohol consumption causes cerebellar degeneration, and the underlying mechanism is unclear. Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain. However, the role of TD in alcohol-induced cerebellar degeneration
Gabrielle Young et al.
Veterinary parasitology, 178(3-4), 346-349 (2011-02-22)
This study evaluated the efficacy of two different doses of amprolium in goats heavily infected with pathogenic Eimeria species. Forty Boer goat kids ranging from 3 to 5 months of age with naturally occurring coccidiosis were randomly divided into 2
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