H3878

Hyodeoxycholic acid

≥98%

• Synonym(s): 3α,6α-Dihydroxy-5β-cholan-24-oic acid
• Empirical Formula (Hill Notation): C₂₄H₄₀O₄
• CAS Number: 83-49-8
• Molecular Weight: 392.57
• EC Number: 201-483-2
• MDL number: MFCD00003681
• UNSPSC Code: 12352106
• PubChem Substance ID: 24895601
• NACRES: NA.77

Properties

• Quality Level: 200
• Assay: ≥98%
• mp: 200-201 °C (lit.)
• SMILES string: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3C[C@H](O)[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C24H40O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17-,18+,19+,20+,21+,23-,24-/m1/s1
• InChI key: DGABKXLVXPYZII-SIBKNCMHSA-N
• Gene Information: human ... NR1H2(7376) , NR1H3(10062)

Description

General description

Hyodeoxycholic acid is a naturally occurring secondary bile acid. It is produced by the gut flora in the small intestine. Hyodeoxycholic acid is obtained from chenodeoxycholic acid during enterohepatic circulation of bile in rats.

Application

Hyodeoxycholic acid has been used:

• as a standard for serum bile acid profiling by liquid chromatography-mass spectrometry (LC-MS) method in rat cells.
• as a component of the growth medium to study its effect as an anti-aging small molecule on the chronological life span (CLS) of the pex5Δ (Δ) strain.
• as a standard for analyzing bile acid composition and total bile acids in mice cells.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves