1370462

Losartan Potassium

United States Pharmacopeia (USP) Reference Standard

• Synonyme(s) : 2-Butyl-4-chloro-1-{[2′-(1H-tetrazol-5-yl)(1,1′-biphenyl)-4-yl]methyl}-1H-imidazole-5-methanol monopotassium salt
• Formule empirique (notation de Hill): C₂₂H₂₂ClKN₆O
• Numéro CAS: 124750-99-8
• Poids moléculaire : 461.00
• Numéro Beilstein : 5845770
• Numéro MDL: MFCD02092704
• Code UNSPSC : 41116107
• ID de substance PubChem : 329750264
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: pharmaceutical primary standard
• Famille d'API: losartan
• Fabricant/nom de marque: USP
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]
• InChI: 1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
• Clé InChI: OXCMYAYHXIHQOA-UHFFFAOYSA-N
• Informations sur le gène: human ... AGTR1(185)

Description

Description générale

Losartan potassium is a new drug used for hypertension. It is nonpeptide angiotensin II (AII) receptor antagonist.

Losartan potassium is nonpeptide angiotensin II (AII) receptor antagonist and is orally active. It belongs to a new class of drugs introduced for clinical trials to treat hypertension.

Application

Losartan potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Losartan Potassium and Hydrochlorothiazide Tablets
• Losartan Potassium Tablets

Actions biochimiques/physiologiques

Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable