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1043706

USP

Aspartame

United States Pharmacopeia (USP) Reference Standard

Synonyme(s) :

Asp-Phe-OMe, N-(L-α-aspartyl)-L-phénylalanine ester méthylique

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About This Item

Formule linéaire :
HOOCCH2CH(NH2)CONHCH(CH2C6H5)COOCH3
Numéro CAS:
22839-47-0
Poids moléculaire :
294.30
Numéro Beilstein :
2223850
Numéro MDL:
MFCD00002724
Code UNSPSC :
41116107
ID de substance PubChem :
329749070
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

aspartame

Fabricant/nom de marque

USP

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O

InChI

1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1

Clé InChI

IAOZJIPTCAWIRG-QWRGUYRKSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aspartame USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Remarque sur l'analyse

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Autres remarques

Sales restrictions may apply.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Aspartame as a preventive agent of chronic toxic effects of ochratoxin A in experimental animals.
E E Creppy et al.
Food additives and contaminants, 13 Suppl, 51-52 (1996-01-01)
T J Maher et al.
Environmental health perspectives, 75, 53-57 (1987-11-01)
The artificial sweetener aspartame (L-aspartyl-L-phenylalanyl-methyl ester), is consumed, primarily in beverages, by a very large number of Americans, causing significant elevations in plasma and, probably, brain phenylalanine levels. Anecdotal reports suggest that some people suffer neurologic or behavioral reactions in
Marina Marinovich et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 60, 109-115 (2013-07-31)
Aspartame is a synthetic sweetener that has been used safely in food for more than 30 years. Its safety has been evaluated by various regulatory agencies in accordance with procedures internationally recognized, and decisions have been revised and updated regularly.
L D Stegink
The American journal of clinical nutrition, 46(1 Suppl), 204-215 (1987-07-01)
Toxicology is based on the premise that all compounds are toxic at some dose. Thus, it is not surprising that very large doses of aspartame (or its components--aspartate, phenylalanine, and methanol) produce deleterious effects in sensitive animal species. The critical
B A Magnuson et al.
Critical reviews in toxicology, 37(8), 629-727 (2007-09-11)
Aspartame is a methyl ester of a dipeptide used as a synthetic nonnutritive sweetener in over 90 countries worldwide in over 6000 products. The purpose of this investigation was to review the scientific literature on the absorption and metabolism, the
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