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V6627

Sigma-Aldrich

Anti-Vascular Endothelial Growth Factor antibody produced in goat

IgG fraction of antiserum, lyophilized powder

Synonyme(s) :

Anti-VEGF

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About This Item

Numéro MDL:
MFCD00282511
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

goat

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

IgG fraction of antiserum

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

lyophilized powder

Espèces réactives

human

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-15 μg/mL
neutralization: suitable
western blot: 1-2 μg/mL

Numéro d'accès UniProt

P15692

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... VEGFA(7422)

Spécificité

The antibody will neutralize the biological activity of recombinant human VEGF165 and recombinant human VEGF121. The antibody shows ~20% cross-reactivity with recombinant mouse VEGF and recombinant rat VEGF.

Immunogène

recombinant human VEGF.

Forme physique

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Notes préparatoires

Purified using protein G.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Markus Theurl et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(9), 4815-4823 (2018-06-20)
The pathogenesis of diabetic neuropathy remains enigmatic. Damage to the vasa nervorum may be responsible for this disorder. Recently, we showed that secretoneurin (SN) induces angiogenesis in hindlimb and myocardial ischemia. Moreover, beneficial effects were observed in wound healing. We
Jertta-Riina Sarkanen et al.
Frontiers in pharmacology, 1, 147-147 (2010-01-01)
The developed standardized human cell based in vitro angiogenesis assay was intra-laboratory pre-validated to verify that the method is reliable and relevant for routine testing of modulators of angiogenesis, e.g., pharmaceuticals and industrial chemicals. This assay is based on the
Ilnur I Salafutdinov et al.
Biomedicines, 11(7) (2023-07-29)
The biosafety of gene therapy remains a crucial issue for both the direct and cell-mediated delivery of recombinant cDNA encoding biologically active molecules for the pathogenetic correction of congenital or acquired disorders. The diversity of vector systems and cell carriers
Laijian Sui et al.
Frontiers in cell and developmental biology, 12, 1374269-1374269 (2024-08-05)
The present study aimed to investigate the involvement of aberrant BMP8A expression in TNBC and bone metastasis. Aberrant expression of BMP8A in breast cancer was first determined by analyzing The Cancer Genome Atlas breast cancer cohort (TCGA-BRCA) and an immunohistochemical
Henning Ulrich et al.
Frontiers in pharmacology, 9, 500-500 (2018-06-06)
Bone marrow metastasis occurs in approximately 350,000 patients that annually die in the U.S. alone. In view of the importance of tumor cell migration into the bone marrow, we have here investigated effects of various concentrations of stromal cell-derived factor-1
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