UC168

(±)-Bufuralol hydrochloride

≥98% (HPLC), solid, β-Adrenoceptor agonist/antagonist

• Synonyme(s) : α-[(tert-Butylamino)methyl]-7-ethyl-2-benzofuranmethanol hydrochloride
• Formule empirique (notation de Hill): C₁₆H₂₃NO₂·HCl
• Numéro CAS: 60398-91-6
• Poids moléculaire : 297.82
• Numéro CE : 262-216-3
• Numéro MDL: MFCD00272648
• Code UNSPSC : 12161501
• ID de substance PubChem : 24724644
• Nomenclature NACRES : NA.77

Propriétés

• product name: (±)-Bufuralol hydrochloride,
• Forme: solid
• Niveau de qualité: 200
• Couleur: white to off-white
• Pf: 143-146 °C
• Solubilité: H₂O: soluble; methanol: soluble
• Température de stockage: 2-8°C
• Chaîne SMILES: Cl.CCc1cccc2cc(oc12)C(O)CNC(C)(C)C
• InChI: 1S/C16H23NO2.ClH/c1-5-11-7-6-8-12-9-14(19-15(11)12)13(18)10-17-16(2,3)4;/h6-9,13,17-18H,5,10H2,1-4H3;1H
• Clé InChI: KJBONRGCLLBWCJ-UHFFFAOYSA-N

Description

Application

CYP2D6 substrate

Actions biochimiques/physiologiques

Bufuralol hydrochloride is known to be a non-specific β-receptor inhibitor that has an affinity for β 1 and β 2 receptors. Furthermore, studies have reported that bufuralol hydrochloride can decrease isoproterenol peripheral resistance.

β-Blocker. Varying β-adrenoceptor agonist/antagonist activity.

Caractéristiques et avantages

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Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Notes préparatoires

(±)-Bufuralol hydrochloride is soluble in water and methanol.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves