T3397

Tylosin solution

solution, suitable for cell culture, BioReagent

• Numéro CAS: 74610-55-2
• Numéro MDL: MFCD07783824
• Code UNSPSC : 12352207
• ID de substance PubChem : 329826751
• Nomenclature NACRES : NA.76

Propriétés

• product name: Tylosin solution, 8 mg/mL in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for cell culture
• Niveau de qualité: 200
• Stérilité: 0.1 μm filtered
• Gamme de produits: BioReagent
• Forme: solution
• Concentration: 8 mg/mL in 0.9% NaCl
• Technique(s): cell culture | mammalian: suitable
• Impuretés: endotoxin, tested
• Couleur: colorless to yellow
• Spectre d'activité de l'antibiotique: Gram-positive bacteria; mycoplasma
• Mode d’action: protein synthesis | interferes
• Température de stockage: 2-8°C
• Chaîne SMILES: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@@H]([C@H]2O)N(C)C)[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@@H]1CO[C@@H]4O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]4OC
• InChI: 1S/C46H77NO17.C4H6O6/c1-13-33-30(22-58-45-42(57-12)41(56-11)37(52)26(5)60-45)18-23(2)14-15-31(49)24(3)19-29(16-17-48)39(25(4)32(50)20-34(51)62-33)64-44-38(53)36(47(9)10)40(27(6)61-44)63-35-21-46(8,55)43(54)28(7)59-35;5-1(3(7)8)2(6)4(9)10/h14-15,17-18,24-30,32-33,35-45,50,52-55H,13,16,19-22H2,1-12H3;1-2,5-6H,(H,7,8)(H,9,10)/b15-14+,23-18+;/t24-,25+,26-,27-,28+,29+,30-,32-,33-,35+,36-,37-,38-,39-,40-,41-,42-,43+,44+,45-,46-;1-,2-/m11/s1
• Clé InChI: ICVKYYINQHWDLM-KBEWXLTPSA-N

Description

Description générale

Chemical structure: macrolide

Tylosin is a macrolide antibiotic, which comprises of a 16-member lactone ring. This solution is recommended for use at 1 mL/L.

Application

Tylosin solution has been used as an antimicrobial agent in antibiotic susceptibility minimal inhibitory concentration(MIC) of E. coli and S. aureus isolates. It has also been used as a component of Dulbecco′s modified Eagle′s (DMEM) medium for self-inactivating lentivirus production and skin fibroblast cultivation.

Actions biochimiques/physiologiques

Tylosin inhibits bacterial protein synthesis by binding to the large subunit 50S. It is effective against Gram-positive bacteria and mycoplasma and is used in veterinary medicine. It has been used to study implant site abscess prevention in cattle and Mycoplasma gallisepticum and Mycoplasma meleagridis infections.

Conditionnement

20ML

Notes préparatoires

This product was formulated to contain 8 mg/ml tylosin in 0.9% sodium chloride.

Stockage et stabilité

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and keep upright to prevent leakage.

Autres remarques

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable