SML1335

Pidotimod

≥98% (HPLC)

• Synonyme(s) : (4R)-3-(5-Oxo-L-prolyl)-1,3-thiazolidine-4-carboxylic acid, (R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid, (R)-3-[(S)-(5-Oxo-2-pyrrolidinyl) carbonyl]-thiazolidine-4-carboxylic acid, 3-L-Pyroglutamyl-L-thiaziolidine-4carboxylic acid, PGT/1A
• Formule empirique (notation de Hill): C₉H₁₂N₂O₄S
• Numéro CAS: 121808-62-6
• Poids moléculaire : 244.27
• Numéro MDL: MFCD00867583
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825793
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Activité optique: [α]/D -135 to -155°, c = 1 in 6 M HCl
• Couleur: white to beige
• Solubilité: H₂O: 2 mg/mL, clear (warmed)
• Température de stockage: room temp
• Chaîne SMILES: OC([C@@H]1CSCN1C([C@H]2NC(CC2)=O)=O)=O
• InChI: 1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1
• Clé InChI: UUTKICFRNVKFRG-WDSKDSINSA-N

Description

Actions biochimiques/physiologiques

Pidotimod is a dipeptide immunostimulant with biological activity on both the adaptive and the innate immune responses. Pidotimod has been reported to modulate airway epithelial cells functions involved in host-virus interaction possibly through NF-kB activation, promote functional maturation of dendritic cells, and facilitate M2 macrophage polarization and function. Pidotimod has been investigated for use to increase response to recurrent respiratory infections primarily in children.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable