SML1087

Sumanirole maleate

≥98% (HPLC)

• Synonyme(s) : (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, CID 9818479 maleate, PNU-95,666 maleate
• Formule empirique (notation de Hill): C₁₁H₁₃N₃O · C₄H₄O₄
• Numéro CAS: 179386-44-8
• Poids moléculaire : 319.31
• Numéro MDL: MFCD09832637
• Code UNSPSC : 12352200
• ID de substance PubChem : 329825464
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Activité optique: [α]/D -22 to -32°, c = 1 in H₂O
• Conditions de stockage: desiccated
• Couleur: white to beige
• Solubilité: H₂O: 10 mg/mL, clear
• Température de stockage: −20°C
• Chaîne SMILES: O=C1N(C[C@H](NC)C2)C3=C2C=CC=C3N1.O=C(O)/C=C\C(O)=O
• InChI: 1S/C11H13N3O.C4H4O4/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9;5-3(6)1-2-4(7)8/h2-4,8,12H,5-6H2,1H3,(H,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m1./s1
• Clé InChI: VOJRMYBBPKNLLI-ORHWHDKWSA-N

Description

Application

Sumanirole maleate has been used as a dopamine type 2 receptor (D2R) agonist to study its effects on spatial learning and memory in rats.

Actions biochimiques/physiologiques

Sumanirole is a highly selective and potent dopamine D2 receptor agonist that decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta. Sumanirole potently stimulates locomotor activity in in animal models of Parkinson′s disease.

Caractéristiques et avantages

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable