SML0737

MitoTEMPO

≥98% (HPLC), powder, antioxidant

• Synonyme(s) : (2-(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium chloride, Mito-TEMPO
• Formule empirique (notation de Hill): C₂₉H₃₅N₂O₂P · Cl
• Numéro CAS: 1334850-99-5
• Poids moléculaire : 510.03
• Code UNSPSC : 12352200
• Nomenclature NACRES : NA.77

Propriétés

• product name: MitoTEMPO, ≥98% (HPLC)
• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated; protect from light
• Couleur: white to light brown
• Solubilité: H₂O: 10 mg/mL, clear
• Température de stockage: −20°C

Description

Application

MitoTEMPO has been used as a mitochondria-targeted antioxidant.

Actions biochimiques/physiologiques

MitoTEMPO is a mitochondrially targeted antioxidant, a specific scavenger of mitochondrial superoxide. MitoTEMPO is a combination of the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, giving MitoTEMPO the ability to pass through lipid bilayers with ease and accumulate several hundred-fold in mitochondria. Mitochondrial dysfunction and oxidative stress contribute to a variety of disorders involving cardiovascular, kidney, liver disorders, Parkinson′s and Alzheimer′s disease.

Autres remarques

Light sensitive

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable