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SMB00081

Sigma-Aldrich

Wogonoside

≥95% (LC/MS-ELSD)

Synonyme(s) :

5,7-Dihydroxy 8-methoxyflavone 7-glucuronide, Glychionide B, Oroxindin, Wogonin 7-glucuronide

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About This Item

Formule empirique (notation de Hill):
C22H20O11
Numéro CAS:
51059-44-0
Poids moléculaire :
460.39
Numéro MDL:
MFCD08704808
Code UNSPSC :
12352205
ID de substance PubChem :
329824759
Nomenclature NACRES :
NA.25

Pureté

≥95% (LC/MS-ELSD)

Forme

solid

Application(s)

metabolomics
vitamins, nutraceuticals, and natural products

Température de stockage

−20°C

Chaîne SMILES 

COc1c(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)cc(O)c3C(=O)C=C(Oc13)c4ccccc4

InChI

1S/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1

Clé InChI

LNOHXHDWGCMVCO-NTKSAMNMSA-N

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Description générale

Natural product derived from plant source.

Actions biochimiques/physiologiques

Wogonoside, a flavanoid, is known for its anti-inflammatory properties. Wogonoside may have therapeutic potential for use in diseases which involve the development of inflammation and angiogenesis through its inhibition of LPS-induced angiogenesis.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Yan Yan et al.
Chinese medicine, 13, 54-54 (2018-11-06)
Microbial fermentation has been widely applied in traditional Chinese medicine (TCM) for thousands of years in China. Various beneficial effects of fermentation for applications in TCM or herbals have been reported, such as enhanced anti-ovarian cancer, antioxidative activity, and neuroprotective
Yan Chen et al.
Toxicology, 259(1-2), 10-17 (2009-05-12)
Wogonoside, one flavonoid derived from the root of Scutellaria baicalensis Georgi, has been reported for its anti-inflammation activity; however, whether it can inhibit inflammation-induced angiogenesis is still unclear. In the present study, we evaluated the effect of wogonoside on lipopolysaccharide
R Xiao et al.
Human & experimental toxicology, 36(11), 1169-1176 (2016-12-13)
Wogonoside is the main flavonoid of the traditional Chinese medicinal herb Scutellaria baicalensis Georgi and has been found to induce growth suppression in myelogenous leukemia cells. However, its activity in T acute lymphoblastic leukemia (T-ALL) is still unclear. In this
Ying Wang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(20-21), 1820-1826 (2009-06-06)
A specific ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method was developed for the simultaneous determination of puerarin, daidzein, baicalin, wogonoside and liquiritin in rat plasma. Chromatographic separation was performed on a C(18) column packed with 1.7 microm particles by a linear
Sujuan Wu et al.
Journal of chromatography. A, 1066(1-2), 243-247 (2005-03-30)
A preparative high-speed counter-current chromatography (HSCCC) method for isolation and purification of baicalin and wogonoside from the Chinese medicinal plant Scutellaria baicalensis Georgi (Huang-qin in Chinese) was successfully established by using ethyl acetate-methanol-1% acetic acid water (5:0.5:5, v/v) as the
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