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Key Documents

SAB5600204

Sigma-Aldrich

Anti-beta-Actin antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM112, purified immunoglobulin

Synonyme(s) :

ACTB, Actin cytoplastic 1, actin beta, beta-actin

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Produit recombinant

expressed in HEK 293 cells

Forme d'anticorps

purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

RM112, monoclonal
recombinant monoclonal

Forme

buffered aqueous glycerol solution

Espèces réactives

all

Technique(s)

ChIP: 1:200
ELISA: suitable (assay dependent concentration)
flow cytometry: suitable (assay dependent concentration)
immunocytochemistry: 1:200
immunohistochemistry: 1:200
immunoprecipitation (IP): 1:200
western blot: 1:1000

Isotype

IgG

Numéro d'accès NCBI

60

Numéro d'accès UniProt

P60709

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... ACTB(60)

Catégories apparentées

Spécificité

This antibody reacts to beta-Actin (Actin, cytoplasmic 1). No cross reactivity with other isoforms of Actin.

Immunogène

A peptide corresponding to the N-terminus of beta-actin

Forme physique

Solution in phosphate buffered saline containing 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Vipul K Singh et al.
Journal of controlled release : official journal of the Controlled Release Society, 349, 796-811 (2022-08-02)
We describe a role of CD44-mediated signaling during host-defense against tuberculosis (TB) using a mouse model of TB and studies in M. tuberculosis (Mtb) infected human macrophage (MФ). Liposomes targeting CD44 using thioaptamers (CD44TA-LIP) were designed and tested as new
Abhishek Mishra et al.
Frontiers in immunology, 13, 859116-859116 (2022-06-01)
GM-CSF is an important cytokine that regulates the proliferation of monocytes/macrophages and its various functions during health and disease. Although growing evidences support the notion that GM-CSF could play a major role in immunity against tuberculosis (TB) infection, the mechanism
Shuhui Wu et al.
Clinical epigenetics, 16(1), 10-10 (2024-01-10)
Metastasis is the primary cause of recurrence and death in patients with papillary thyroid carcinoma (PTC). LncRNA ACTA2-AS1, a long non-coding RNA, acts as a tumor suppressor in multiple types of human malignancies, while the role of ACTA2-AS1 in PTC
Chung-Chih Tseng et al.
Scientific reports, 12(1), 10513-10513 (2022-06-23)
Oral squamous cell carcinoma (OSCC) is a common malignant tumor worldwide that is characterized by abnormal lesions or malignant hyperplasia of soft and hard tissues in the oral cavity. Previous research has found that HDAC6 may be a potential therapeutic
Serena Colafrancesco et al.
Arthritis & rheumatology (Hoboken, N.J.), 74(4), 654-664 (2021-11-09)
Salivary gland epithelial cells (SGECs) are key cellular drivers in the pathogenesis of primary Sjögren's syndrome (SS); however, the mechanisms sustaining SGEC activation in primary SS remain unclear. We undertook this study to determine the role of autophagy in the
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