SAB4502609

Anti-NF-κB p65 antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : NFKB3, RELA, TF65, nuclear factor NF-κ-B p65 subunit, p65
• Numéro MDL: MFCD00802848
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 60 kDa
• Espèces réactives: human, mouse
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:20000; western blot: 1:500-1:1000
• Numéro d'accès NCBI: Q04206
• Numéro d'accès UniProt: Q04206
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... RELA(5970)

Description

Description générale

Anti-NF-κB p65 antibody detects endogenous levels of total NF-κB p65 protein.

The NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) gene is mapped to human chromosome 11q13.1. It codes for a transcription factor, a subunit of NF-κB.

Immunogène

The antiserum was produced against synthesized peptide derived from human NF-kappaB p65.

Immunogen Range: 278-327

Application

Anti-NF-κB p65 antibody produced in rabbit has been used in western blot analysis.

Actions biochimiques/physiologiques

NF-κB p65 (nuclear factor κ-light-chain-enhancer of activated B cells p65) is associated with many fibrotic diseases such as liver fibrosis and cardiac fibrosis. Cell proliferation, inflammation, and apoptosis are some of the processes mediated by NF-κB p65. Dysregulation of the gene results in chronic inflammatory diseases, autoimmune disorders and cancer. NF-κB p65 plays an important role in NF-κB signaling.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable