SAB5700333

Anti-Phospho-NF-kB p65-S276 antibody produced in rabbit

• Synonyme(s) : CMCU, NF-kB p65, NFKB3, RELA, p65
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.43

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: 58; 59; 60
• Espèces réactives: human, rat, mouse
• Concentration: 0.95mg/ml
• Technique(s): immunofluorescence: 1:20-1:50; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:2000
• Numéro d'accès UniProt: Q04206
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pSer276 )
• Informations sur le gène: human ... RELA(5970)

Description

Description générale

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Immunogène

A synthetic phosphorylated peptide around S276 of human NF-kB p65 (NP_068810.3).

Forme physique

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Stockage et stabilité

Store at -20℃. Avoid freeze / thaw cycles.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable