SAB4500814

Anti-Estrogen Receptor-β antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : ESR2, ESTRB, Estrogen receptor β, NR3A2
• Numéro MDL: MFCD01323253
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 59 kDa
• Espèces réactives: human, rat, mouse
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:1000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• Numéro d'accès NCBI: Q92731
• Numéro d'accès UniProt: Q92731
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ESR2(2100)

Description

Description générale

Estrogen Receptor-β (ERβ) is a member of the nuclear receptor superfamily. It has nine exons and is mapped to human chromosome 14q23.2.

Anti-Estrogen Receptor-β Antibody detects endogenous levels of total Estrogen Receptor-β protein.

Immunogène

The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-beta.

Immunogen Range: 71-120

Application

Anti-Estrogen Receptor-βantibody has been used in western blotting .{42,43}

Actions biochimiques/physiologiques

Estrogen Receptor-β (ERβ) is involved in immune and inflammatory response. In females, estrogen receptor β (ESR2) is expected to play an important role in the progress of MDD (major depressive disorder). Aberrations in ESR2 gene result in bone mineral density variation.

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): nwg
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable