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Principaux documents

SAB4200230

Sigma-Aldrich

Anti-DPP4/CD26 antibody, Mouse monoclonal

clone A6H, purified from hybridoma cell culture

Synonyme(s) :

Monoclonal Anti-ADABP, Monoclonal Anti-ADCP2, Monoclonal Anti-DPPIV, Monoclonal Anti-TP103, Monoclonal Anti-dipeptidyl-peptidase 4

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Sélectionner une taille de conditionnement

100 MG
262,10 €
250 MG
357,00 €
500 MG
609,20 €
1 G
769,10 €
2.5 G
1 464,60 €
5 G
2 144,50 €
10 G
3 159,80 €

Vendor SKU: EN300-306493-100MG

262,10 €


Disponibilité
Expédition sous 14 jour(s) - par un Aldrich Partner.

To order products, please contact your local dealer.

Sélectionner une taille de conditionnement

Changer de vue
100 MG
262,10 €
250 MG
357,00 €
500 MG
609,20 €
1 G
769,10 €
2.5 G
1 464,60 €
5 G
2 144,50 €
10 G
3 159,80 €

About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Vendor SKU: EN300-306493-100MG

262,10 €


Disponibilité
Expédition sous 14 jour(s) - par un Aldrich Partner.

To order products, please contact your local dealer.

Source biologique

mouse

Conjugué

unconjugated

Forme d'anticorps

purified from hybridoma cell culture

Type de produit anticorps

primary antibodies

Clone

A6H, monoclonal

Forme

buffered aqueous solution

Espèces réactives

human

Concentration

~4.0 mg/mL

Technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
indirect immunofluorescence: 20-40 μg/mL using methanol/acetone fixed HT-29 cells

Isotype

IgG1

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Cet article
PHL86416PHL89286PHL89583
(−)-Borneol phyproof® Reference Substance

PHL89583

(−)-Borneol

grade

primary reference standard

grade

-

grade

primary reference standard

grade

primary reference standard

assay

≥90.0% (HPLC)

assay

≥98.0% (HPLC)

assay

≥90.0% (GC)

assay

≥95.0% (GC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

manufacturer/tradename

PhytoLab

manufacturer/tradename

PhytoLab

manufacturer/tradename

PhytoLab

manufacturer/tradename

PhytoLab

product line

phyproof® Reference Substance

product line

phyproof® Reference Substance

product line

phyproof® Reference Substance

product line

phyproof® Reference Substance

Description générale

Monoclonal Anti-DPP4/CD26 (mouse IgG1 isotype) is derived from the hybridoma A6H produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with human fetal homogenates. Dipeptidyl peptidase-4 (DPP4) belongs to the S9B protein family, which cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides and peptide hormones. It is a type II transmembrane glycoprotein, expressed on the surface of many cell types.

Immunogène

human fetal homogenates.

Application

Monoclonal Anti-DPP4/CD26 antibody produced in mouse has been used in:
  • enzyme linked immuno sorbent assay (ELISA)
  • immunocytochemistry
  • immunohistochemistry
  • flow cytometry

Actions biochimiques/physiologiques

Dipeptidyl peptidase-4 (DPP4) is involved in the regulation of the biological activity of hormones and chemokines, such as glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide. DPP4 inhibition maybe used to treat type 2 diabetes mellitus. It acts as a T cell activation molecule and regulates immunity and immune-mediated disorders.

Forme physique

Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Dipeptidyl peptidase-4 (CD26): knowing the function before inhibiting the enzyme
Matteucci E and Giampietro O
Current Medicinal Chemistry, 16(23), 2943-2951 (2009)
R L Vessella et al.
Cancer research, 45(12 Pt 1), 6131-6139 (1985-12-01)
Monoclonal antibodies (MABs) reactive with human renal cell carcinoma (RCC) were generated following immunization of mice with either RCC homogenates, RCC cell lines, or fetal kidney homogenates. The characteristics of four highly reactive immunoglobulin G1 MABs, designated UMVA-RCC-A6H, UMVA-RCC-A36, UMVA-RCC-C5H
Vlad Tocan et al.
The Journal of biological chemistry, 297(6), 101354-101354 (2021-11-01)
Hepatocytes differ from columnar epithelial cells by their multipolar organization, which follows the initial formation of central lumen-sharing clusters of polarized cells as observed during liver development and regeneration. The molecular mechanism for hepatocyte polarity establishment, however, has been comparatively

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