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Key Documents

R3756

Sigma-Aldrich

Anti-Rat IgG (whole molecule) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

Numéro MDL:
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

rabbit

Niveau de qualité

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Technique(s)

indirect ELISA: 1:90,000

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

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Description générale

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. There are five different types of Immunoglobulins. Each immunoglobin have two heavy (H) and two light (L) chains held together by disulfide linkages. Each light chain comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region. The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.

Application

Anti-Rat IgG (whole molecule) antibody produced in rabbit has been used in:
  • ADA immunoassay
  • immunohistochemistry
  • fluorescence-activated cell sorting (FACS)

Actions biochimiques/physiologiques

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.

Autres remarques

Antibody adsorbed with human IgG.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificats d'analyse (COA)

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Dopaminergic drug-induced modulation of the expression of the dopamine transporter in peripheral blood lymphocytes in Parkinson?s disease
Fanciulli A, et al.
Pharmacological Reports, 63(4), 1056-1060 (2011)
Universal immunoassay applied during early development of large molecules to understand impact of immunogenicity on biotherapeutic exposure
Bautista AC, et al.
The AAPS Journal, 14(4), 843-849 (2012)
The primate thalamus is a key target for brain dopamine
Sanchez-Gonzalez M, et al.
Journal of neurosciences in rural practice, 25(26), 6076-6083 (2005)
Hubert Lam et al.
Infection and immunity, 82(9), 3764-3774 (2014-06-25)
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The Plant cell, 24(4), 1626-1642 (2012-05-02)
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