P9625

Phenazine methosulfate

powder, electron acceptor

• Synonyme(s) : 5-Methylphenazinium methyl sulfate, N-Methylphenazonium methyl sulfate, PMS
• Formule linéaire : C₁₃H₁₁N₂ · CH₃SO₄
• Numéro CAS: 299-11-6
• Poids moléculaire : 306.34
• Numéro Beilstein : 3898869
• Numéro CE : 206-072-1
• Numéro MDL: MFCD00011923
• Code UNSPSC : 12352200
• ID de substance PubChem : 24899045
• Nomenclature NACRES : NA.77

Propriétés

• product name: Phenazine methosulfate,
• Forme: powder
• Niveau de qualité: 200
• λ: 0.01 g/L in H₂O, 1 cm path
• Absorption UV: λ: 387.5 nm A_max
• Spectre d'activité de l'antibiotique: fungi
• Mode d’action: DNA synthesis | interferes; cell membrane | interferes
• Température de stockage: −20°C
• Chaîne SMILES: COS([O-])(=O)=O.C[n+]1c2ccccc2nc3ccccc13
• InChI: 1S/C13H11N2.CH4O4S/c1-15-12-8-4-2-6-10(12)14-11-7-3-5-9-13(11)15;1-5-6(2,3)4/h2-9H,1H3;1H3,(H,2,3,4)/q+1;/p-1
• Clé InChI: RXGJTUSBYWCRBK-UHFFFAOYSA-M

Description

Description générale

Phenazines are heterocyclic compounds produced as secondary metabolites by bacteria.

Application

Phenazine methosulfate is used with ascorbic acid to determine nitric oxide reductase activity.
Phenazine methosulfate has been used:

• as a component of succinate dehydrogenase enzyme substrate solution
• to induce superoxide radical generation in red blood cell suspensions and to study its influence on RBC deformability
• as a component of complex II histochemistry media

Actions biochimiques/physiologiques

Phenazine m ethosulfate (PMS) acts as a good electron acceptor. PMS is reduced non-enzymatically by (nicotinamide adenine dinucleotide) NADH and (nicotinamide adenine dinucleotide phosphate) NADPH.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves