Yes. See Biochem Biophys Res Commun. 1988 Feb 15;150(3):1294-301.
I8377
Iodonitrotetrazolium chloride
Used in colorimetric assays.
Synonyme(s) :
2-(4-Iodophenyl)-3-(4-nitrophenyl)-5-phenyl-2H-tetrazolium chloride, p-Iodonitrotetrazolium Violet, INT
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About This Item
Formule empirique (notation de Hill):
C19H13ClIN5O2
Numéro CAS:
Poids moléculaire :
505.70
Beilstein:
4093224
Numéro CE :
Numéro MDL:
Code UNSPSC :
12171500
ID de substance PubChem :
Nomenclature NACRES :
NA.47
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Produits recommandés
Niveau de qualité
Essai
≥98% (TLC)
Forme
powder
Pf
240 °C (dec.) (lit.)
Solubilité
H2O: 4 mg/mL
Application(s)
diagnostic assay manufacturing
hematology
histology
Température de stockage
2-8°C
Chaîne SMILES
[Cl-].[O-][N+](=O)c1ccc(cc1)-[n+]2nc(nn2-c3ccc(I)cc3)-c4ccccc4
InChI
1S/C19H13IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27;/h1-13H;1H/q+1;/p-1
Clé InChI
JORABGDXCIBAFL-UHFFFAOYSA-M
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Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Mention d'avertissement
Danger
Mentions de danger
Conseils de prudence
Classification des risques
Flam. Sol. 1 - STOT SE 3
Organes cibles
Respiratory system
Code de la classe de stockage
4.1B - Flammable solid hazardous materials
Classe de danger pour l'eau (WGK)
WGK 3
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Is there a procedure for reducing Product I8377, Iodonitrotetrazolium chloride, by superoxide radicals?
1 answer-
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Product I8377, Iodonitrotetrazolium chloride, is stated to have solubility in water, ethanol and ethylene glycol monomethylether. What other solutions can be used?
1 answer-
Conn's Biological Stains, 10th Edition (page 163) states P-Iodonitrotetrazolium Violet is also soluble in dimethylsulfoxide and dimethylsulfoxide-water mixtures.
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Can Product I8377, Iodonitrotetrazolium chloride, be used for the staining of cells?
1 answer-
Yes, although due to the large crystal size of the formazan and lack of substantivity, histological application of I8377 has been limited. In microbiology, the product was used by Lussenhop and Fogel (1993) for in situ microscopic observation of soil biota.. Gribbon and Barer (1995) used for the demonstration of viable but nonculturable bacteria. Heidelberg (1997) used as a bacterial viability stain.
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Is Product I8377, Iodonitrotetrazolium chloride, lipophilic?
1 answer-
Yes, I8377 is a lipophilic cation of moderate size. The resulting formazan is more strongly liophilic and fat soluble.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Is there a reference for using Product I8377, Iodonitrotetrazolium chloride, to treat brain membrane preparations?
1 answer-
Yes. See Neuroscience Letters Volume 35, Issue 2, 21 February 1983, Pages 215-220
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