P0869

Monoclonal Anti-Peroxisome Proliferator Activated Receptor α antibody produced in mouse

~1 mg/mL, clone 3B6/PPAR, purified immunoglobulin, buffered aqueous solution

• Synonyme(s) : Anti-PPARα
• Numéro MDL: MFCD01092469
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: mouse
• Niveau de qualité: 200
• Conjugué: unconjugated
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: 3B6/PPAR, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: mouse, rat, human
• Concentration: ~1 mg/mL
• Technique(s): western blot: 2-5 μg/mL using human, mouse and rat
• Isotype: IgG2b
• Numéro d'accès UniProt: Q07869
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... PPARA(5465) ; mouse ... Ppara(19013) ; rat ... Ppara(25747)

Description

Description générale

Peroxisome proliferator-activated receptors (PPARs) are a group of closely related nuclear receptors. Three PPAR isotypes have been identified: α,β (also called NUC1) and γ. PPARa mRNA is expressed most in brown adipose tissue, heart, liver and kidney in rats. The gene encoding PPARα is localized on human chromosome 22q12-q13.1 and rat chromosome 7q34.

Immunogène

purified recombinant PPARα protein.

Actions biochimiques/physiologiques

Peroxisome proliferator-activated receptors (PPARs) may be involved in chronic diseases such as diabetes, obesity, atherosclerosis and cancer. PPARα has a protective function in fatty acids overload associated tubular injury. The enzyme also has a role in fatty acid oxidation and metabolism.

Forme physique

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable