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N8133

Sigma-Aldrich

Nerve Growth Factor from Vipera lebetina venom

lyophilized powder, suitable for cell culture

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About This Item

Numéro CAS:
9061-61-4
Numéro MDL:
MFCD00147703
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.77

product name

Nerve Growth Factor from Vipera lebetina venom, NGF, lyophilized powder, suitable for cell culture

Source biologique

Vipera Lebetina

Niveau de qualité

200

Forme

lyophilized powder

Puissance

0.2-20 μg/mL ED50/EC50

Qualité

endotoxin tested

Poids mol.

protein 32.5 kDa

Conditionnement

pkg of 0.1 mg

Technique(s)

cell culture | mammalian: suitable

Impuretés

<10 EU/vial

Couleur

white to off-white

Numéro d'accès UniProt

P25428

Température de stockage

−20°C

Catégories apparentées

Forme physique

Lyophilized from a 0.2 μm filtered solution in sodium acetate buffer.

Notes préparatoires

Isolated from the snake venom of V. lebetina.

Remarque sur l'analyse

The biological activity of Nerve Growth Factor (NGF) from Vipera lebetina venom is measured in a cell proliferation assay using PC-12 cells.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Giusi Prencipe et al.
Journal of immunology (Baltimore, Md. : 1950), 192(7), 3345-3354 (2014-03-04)
Nerve growth factor (NGF) levels are highly increased in inflamed tissues, but their role is unclear. We show that NGF is part of a regulatory loop in monocytes: inflammatory stimuli, while activating a proinflammatory response through TLRs, upregulate the expression
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Science (New York, N.Y.), 346(6209), 641-646 (2014-11-02)
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand Spaetzle is not thought to have a vertebrate equivalent. We have found that the structurally related cystine-knot protein, nerve growth factor
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Cell, 152(5), 945-956 (2013-03-05)
A growing number of studies are revealing that cells can send and receive information by controlling the temporal behavior (dynamics) of their signaling molecules. In this Review, we discuss what is known about the dynamics of various signaling networks and
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(24), 10066-10074 (2013-06-14)
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Trk neurotrophin receptor ubiquitination in response to ligand activation regulates signaling, trafficking, and degradation of the receptors. However, the in vivo consequences of Trk ubiquitination remain to be addressed. We have developed a mouse model with a mutation in the
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