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M4879

Sigma-Aldrich

3-O-Methyl-D-glucopyranose

≥98% (GC)

Synonyme(s) :

3-O-Methyl-α-D-glucopyranose, 3-O-Methylglucose

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About This Item

Formule empirique (notation de Hill):
C7H14O6
Numéro CAS:
13224-94-7
Poids moléculaire :
194.18
Numéro CE :
236-197-7
Numéro MDL:
MFCD00063266
Code UNSPSC :
12352201
ID de substance PubChem :
24896954
Nomenclature NACRES :
NA.25

Niveau de qualité

200

Pureté

≥98% (GC)

Forme

powder

Activité optique

[α]25/D 55 to 57 °, c = 1% (w/v) in water + trace NH4OH

Technique(s)

gas chromatography (GC): suitable

Pf

167-169 °C (lit.)

Solubilité

water: 50 mg/mL, clear to slightly hazy, colorless

Chaîne SMILES 

CO[C@@H]1[C@@H](O)[C@@H](O)O[C@H](CO)[C@H]1O

InChI

1S/C7H14O6/c1-12-6-4(9)3(2-8)13-7(11)5(6)10/h3-11H,2H2,1H3/t3-,4-,5-,6+,7+/m1/s1

Clé InChI

SCBBSJMAPKXHAH-OVHBTUCOSA-N

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Description générale

3-O-Methyl-D-glucopyranose is a passive carrier-mediated transported glucose analogue.

Application

Varying concentrations of 3-O-methyl-D-glucopyranose were used to measure responses of jejunal and ileal short circuit currents to determine maximal transport capacity and carrier affinity in a study to assess intestinal glucose transport in rats with diabetes mellitus. It has also been used in a study to investigate nonmetabolizable glucose analogues and ornithine decarboxylase expression in LLC-PK1 cells.

Autres remarques

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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R N Fedorak et al.
Canadian journal of physiology and pharmacology, 69(8), 1143-1148 (1991-08-01)
Chronic diabetes enhances intestinal absorption of glucose and induces hyperphagia. We examined the enhanced intestinal absorption of glucose in ad libitum-fed rats with streptozocin-induced diabetes mellitus and compared these results with those obtained from pair-fed diabetic animals. Maximal transport capacity
Nam Q Nguyen et al.
Obesity surgery, 26(1), 77-84 (2015-05-20)
The aim was to determine the effects of fat and protein preloads on pouch emptying (PE), caecal arrival time (CAT), glucose absorption, blood glucose (BSL), gut hormones, haemodynamics and gastrointestinal (GI) symptoms in subjects who had undergone Roux-en-Y gastric bypass
Asaf Miller et al.
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 19(1), 37-42 (2017-02-22)
To evaluate the effect of exogenous glucagonlike peptide-1 (GLP-1) on small intestinal glucose absorption and blood glucose concentrations during critical illness. A prospective, blinded, placebo-controlled, cross-over, randomised trial in a mixed medical-surgical adult intensive care unit, with 12 mechanically ventilated
Anna E Di Bartolomeo et al.
Critical care (London, England), 16(5), R167-R167 (2012-09-19)
Studies in the critically ill that evaluate intragastric and post-pyloric delivery of nutrient have yielded conflicting data. A limitation of these studies is that the influence in the route of feeding on glucose absorption and glycaemia has not been determined.
D W Lundgren et al.
The American journal of physiology, 259(4 Pt 1), C647-C653 (1990-10-01)
This report examines the effect of nonmetabolizable glucose analogues on ornithine decarboxylase (ODC) activity in LLC-PK1 cells. The addition of Na(+)-dependent cotransported glucose analogues, 1-O-methyl-alpha-D-glucopyranoside (alpha-MDG) and 1-O-methyl-beta-D-glucopyranoside, to Earle's balanced salt solution minus glucose (EBSS-G) increased ODC activity five-
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