M104

(±)-Muscarine chloride hydrate

≥98% (HPLC)

• Synonyme(s) : Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate
• Formule empirique (notation de Hill): C₉H₂₀ClNO₂ · xH₂O
• Numéro CAS: 2936-25-6
• Poids moléculaire : 209.71 (anhydrous basis)
• Numéro MDL: MFCD00055067
• Code UNSPSC : 12352200
• ID de substance PubChem : 24278578
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Pureté: ≥98% (HPLC)
• Forme: powder
• Conditions de stockage: desiccated
• Couleur: white
• Solubilité: deionized water: ≥20 mg/mL
• Température de stockage: room temp
• Chaîne SMILES: [Cl-].CC1OC(CC1O)C[N+](C)(C)C
• InChI: 1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1
• Clé InChI: WUFRNEJYZWHXLC-UHFFFAOYSA-M
• Informations sur le gène: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

Description

Application

(±)-Muscarine chloride hydrate may be used:

• as an acetylcholine receptor agonist in neuronal precursor cell lines PC 12 cells
• as toxin test compound for paper spray mass spectrometry (PSMS) optimization experiments
• as a component of quality control(QC) in hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry (HILIC-HRMS/MS) analysis of human urine samples

Actions biochimiques/physiologiques

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.

Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.

Caractéristiques et avantages

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302,H319
• Conseils de prudence: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Classification des risques: Acute Tox. 4 Oral - Eye Irrit. 2
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: dust mask type N95 (US), Eyeshields, Gloves