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LO3300

Sigma-Aldrich

LOPAC®1280 (International Version)

Synonyme(s) :

Library of Pharmacologically Active Compounds

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About This Item

Code UNSPSC :
41106609
Nomenclature NACRES :
NA.77

Forme

liquid

Niveau de qualité

100

Conditions d'expédition

dry ice

Température de stockage

−20°C

Description générale

Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (250 μl at 10 mM in DMSO in archival storage racks).

Application

LOPAC®1280 (International Version) has been used to screen chemical inhibitors with dephosphorylation activity. It has also been used in MyoScreen myotubes to screen for muscle regeneration molecules.

Caractéristiques et avantages

Collection of approximately 1,280 pharmacologically active Sigma compounds.
Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience:

  • Apotosis
  • G Proteins & Cyclic Nucleotides
  • Gene Regulation & Expression
  • Ion Channels
  • Lipid Signaling
  • Multi-drug Resistance
  • Neurotransmission
  • Phosphorylation
SDFile provided to construct a database containing:

  • Structure
  • Primary Name
  • Secondary Name
  • Pharmacological Activity
  • Sigma-RBI Product Number (for easy re-order)
  • Rack Position

Autres remarques

For sale outside of the U.S. only. U.S. customers should refer to Product Code LO1280.

Informations légales

LOPAC is a registered trademark of Merck KGaA, Darmstadt, Germany

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 2

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Point d'éclair (°F)

188.6 °F - closed cup

Point d'éclair (°C)

87 °C - closed cup

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Molecular Cell, 67(5), 783-798 (2017)
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Journal of biomolecular screening, 19(7), 1060-1069 (2014-03-13)
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The lysine acetyltransferase (KAT) Rtt109 forms a complex with Vps75 and catalyzes the acetylation of histone H3 lysine 56 (H3K56ac) in the Asf1-H3-H4 complex. Rtt109 and H3K56ac are vital for replication-coupled nucleosome assembly and genotoxic resistance in yeast and pathogenic
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Epigenetic modifications play a crucial role in human diseases. Unlike genetic mutations, however, they do not change the underlying DNA sequences. Epigenetic phenomena have gained increased attention in the field of cancer research, with many studies indicating that they are
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Explore compound library screening options with our Pharmacologically Active Compounds portfolio.

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Explore compound library screening options with our Pharmacologically Active Compounds portfolio.

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