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I2879

Sigma-Aldrich

Inosine 5′-monophosphate from Saccharomyces cerevisiae

≥98%

Synonyme(s) :

I-5′-P, IMP, Inosinic Acid

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About This Item

Formule empirique (notation de Hill):
C10H13N4O8P
Numéro CAS:
131-99-7
Poids moléculaire :
348.21
Numéro CE :
205-045-1
Numéro MDL:
MFCD00066754
Code UNSPSC :
41106305
ID de substance PubChem :
24896014
Nomenclature NACRES :
NA.51

Niveau de qualité

200

Pureté

≥98%

Forme

powder

Solubilité

water: 100 mg/mL, clear to slightly hazy, colorless to almost colorless

Température de stockage

−20°C

Chaîne SMILES 

CC1(OCP(O)(O)=O)[C@@](O)(C)[C@@](C)(O)[C@@](N(C=N2)C3=C2C(NC=N3)=O)(C)O1

InChI

1S/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)

Clé InChI

GRSZFWQUAKGDAV-UHFFFAOYSA-N

Application

Inosine 5′-monophosphate (IMP) has been used as an umami tastant along with MSG to study their cortical responses and interactions in the human brain. It may be used as a substrate to study the distribution, specificity, and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).

Actions biochimiques/physiologiques

Inosine 5′-monophosphate is a purine nucleotide with a flavor-enhancing property. It acts as a precursor for the synthesis of both guanosine monophosphate (GMP) and adenosine monophosphate (AMP).

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Yuichi Yasutake et al.
Journal of gastroenterology and hepatology, 32(11), 1839-1845 (2017-03-16)
Uric acid is excreted from blood into the intestinal lumen, yet the roles of uric acid in intestinal diseases remain to be elucidated. The study aimed to determine whether uric acid could reduce end points associated with nonsteroidal anti-inflammatory drug
Christine M Ordija et al.
American journal of physiology. Lung cellular and molecular physiology, 312(6), L1018-L1028 (2017-04-08)
Lung injury can release intracellular actin into the alveolar milieu and is also associated with increased susceptibility to secondary infections. We investigated the effect of free (extracellular) actin on lung macrophage host defense functions. Western blot analysis demonstrated free actin
Haruhiko Oda et al.
Neurology, 81(20), 1741-1745 (2013-10-15)
To compare the usefulness of brain perfusion SPECT and (123)I-metaiodobenzylguanidine ((123)I-MIBG) in predicting the conversion of possible dementia with Lewy bodies (DLB) to probable DLB. We examined 94 patients with possible DLB based on the Consensus Criteria for the Clinical
Vivek Vinod et al.
Biochimica et biophysica acta. General subjects, 1865(1), 129758-129758 (2020-10-09)
Bacterial surface proteins act as potential adhesins or invasins. The GroEL is a signal peptide-free surface expressed protein that aids adhesion in Escherichia coli by binding to LOX-1 receptor of the host cells. Mycobacterium tuberculosis (Mtb) expresses GroEL2 protein, having
H Mori et al.
Applied microbiology and biotechnology, 48(6), 693-698 (1998-02-11)
A novel process for producing inosine 5'-monophosphate (5'-IMP) has been demonstrated. The process consists of two sequential bioreactions; the first is a fermentation of inosine by a mutant of Corynebacterium ammoniagenes, and the second is a unique phosphorylating reaction of
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