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H9267

Sigma-Aldrich

Heparin disaccharide I-S sodium salt

sulfated heparin fragment

Synonyme(s) :

α-ΔUA-2S-[1→4]-GlcNS-6S

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About This Item

Formule linéaire :
C12H15NO19S3Na4
Numéro CAS:
136098-10-7
Poids moléculaire :
665.40
Numéro MDL:
MFCD00466927
Code UNSPSC :
12352201
ID de substance PubChem :
24895847
Nomenclature NACRES :
NA.25

Niveau de qualité

200

Pureté

≥98%

Forme

powder

Technique(s)

HPLC: suitable

Température de stockage

−20°C

Chaîne SMILES 

[Na].OC(COS(O)(=O)=O)C(OC1OC(=CC(O)C1OS(O)(=O)=O)C(O)=O)C(O)C(NS(O)(=O)=O)C=O

InChI

1S/C12H19NO19S3.Na.H/c14-2-4(13-33(20,21)22)8(17)9(6(16)3-29-34(23,24)25)31-12-10(32-35(26,27)28)5(15)1-7(30-12)11(18)19;;/h1-2,4-6,8-10,12-13,15-17H,3H2,(H,18,19)(H,20,21,22)(H,23,24,25)(H,26,27,28);;

Clé InChI

QNESCZPGLNWDJH-UHFFFAOYSA-N

Actions biochimiques/physiologiques

Products of the digestion of heparin and heparan sulfate by various heparinases

Autres remarques

In the following listings, ΔUA = 4-deoxy-L-threo-hex-4-enopyranosyluronic acid; GlcN = D-glucosamine; Ac = Acetyl; NS, 2S, 6S, = N-sulfo, 2-sulfate and 6-sulfate respectively.
To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Notes préparatoires

Produced by the action of heparinase I and II

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Yi Xue et al.
The Journal of biological chemistry, 286(34), 29748-29757 (2011-07-01)
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Julia P Steringer et al.
eLife, 6 (2017-07-20)
FGF2 is secreted from cells by an unconventional secretory pathway. This process is mediated by direct translocation across the plasma membrane. Here, we define the minimal molecular machinery required for FGF2 membrane translocation in a fully reconstituted inside-out vesicle system.
Hector Moreno et al.
PLoS neglected tropical diseases, 14(12), e0009004-e0009004 (2020-12-29)
A detailed understanding of the mechanisms underlying the capacity of a virus to break the species barrier is crucial for pathogen surveillance and control. New World (NW) mammarenaviruses constitute a diverse group of rodent-borne pathogens that includes several causative agents

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