H8892

Heparin disaccharide I-H sodium salt

• Synonyme(s) : α-ΔUA-2S-[1→4]-GlcN-6S
• Formule linéaire : C₁₂H₁₇NO₁₆S₂Na₂
• Numéro CAS: 136098-04-9
• Poids moléculaire : 541.37
• Numéro MDL: MFCD00466926
• Code UNSPSC : 12352201
• ID de substance PubChem : 329815254
• Nomenclature NACRES : NA.25

Propriétés

• Pureté: ~99% (HPLC)
• Forme: solid
• Technique(s): HPLC: suitable
• Couleur: white to faint yellow
• Température de stockage: −20°C
• Chaîne SMILES: [Na+].[Na+].[Na+].N[C@H]1C(O)O[C@H](COS([O-])(=O)=O)[C@@H](O[C@@H]2OC(=C[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@@H]1O
• InChI: 1S/C12H19NO16S2.3Na/c13-6-7(15)9(5(26-11(6)18)2-25-30(19,20)21)28-12-8(29-31(22,23)24)3(14)1-4(27-12)10(16)17;;;/h1,3,5-9,11-12,14-15,18H,2,13H2,(H,16,17)(H,19,20,21)(H,22,23,24);;;/q;3*+1/p-3/t3-,5+,6+,7+,8+,9+,11?,12-;;;/m0.../s1
• Clé InChI: WHYGSGRAJJCXLY-LXROVJCJSA-K

Description

Application

Heparin disaccharide I-H sodium salt has been used as a non-naphthalene, negatively charged, bivalent compound to test its ability to induce liquid-liquid phase separation (LLPS).

Actions biochimiques/physiologiques

Heparin disaccharide is a bivalent compound with less hydrophobic nature. It elevates the cytosolic calcium (Ca²⁺) extrusion rate and may serve as a potential drug for the activation of Na+ /Ca²⁺ exchanger (NCX).

Products of the digestion of heparin and heparan sulfate by various heparinases

Autres remarques

In the following listings, ΔUA = 4-deoxy-L-threo-hex-4-enopyranosyluronic acid; GlcN = D-glucosamine; Ac = Acetyl; NS, 2S, 6S, = N-sulfo, 2-sulfate and 6-sulfate respectively.

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)