G5146

D-(+)-Glucose

Hybri-Max^™, powder, BioReagent, suitable for hybridoma

• Synonyme(s) : Dextrose
• Formule empirique (notation de Hill): C₆H₁₂O₆
• Numéro CAS: 50-99-7
• Poids moléculaire : 180.16
• Numéro Beilstein : 1724615
• Numéro CE : 200-075-1
• Numéro MDL: MFCD00063774
• Code UNSPSC : 12352201
• ID de substance PubChem : 24895199
• Nomenclature NACRES : NA.75

Propriétés

• Source biologique: maize
• Niveau de qualité: 200
• Qualité: Hybri-Max^™
• Gamme de produits: BioReagent
• Pureté: ≥99.5%
• Forme: powder
• Technique(s): cell culture | hybridoma: suitable
• Impuretés: endotoxin, tested
• Pf: 150-152 °C (lit.)
• Solubilité: H₂O: 2g + 15 mL (Tested)
• Chaîne SMILES: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• Clé InChI: WQZGKKKJIJFFOK-DVKNGEFBSA-N
• Informations sur le gène: human ... PYGM(5837)

Description

Description générale

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively. The PYGM gene is mapped to human chromosome 11q13.1.

Application

D-(+)-Glucose has been used in cell engineering. It has also been used to perform oral glucose tolerance test.

Actions biochimiques/physiologiques

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia. Mutation in PYGM leads to McArdle disease, a glycogen storage disorder. The PYGM gene is significantly associated with energy production.

Notes préparatoires

The material may produce a yellowish solution if prepared at a higher concentration than 2g + 15ml.

Informations légales

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)