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F9887

Sigma-Aldrich

Anti-Rabbit IgG (whole molecule)–FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonyme(s) :

Goat Anti-Rabbit IgG (whole molecule)–Fluorescein isothiocyanate

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About This Item

Numéro MDL:
MFCD00162786
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.46

Source biologique

goat

Niveau de qualité

200

Conjugué

FITC conjugate

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

secondary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Contient

≥15 mM sodium azide as preservative

Conditions de stockage

protect from light

Technique(s)

direct immunofluorescence: 1:160
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:160

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

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Description générale

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids.
There are four classes of IgG namely IgG1, IgG2, IgG3, and IgG4. Among them IgG1 is the most abundant antibody.

Spécificité

Binds all rabbit Igs.

Immunogène

Purified rabbit IgG

Application

Anti-Rabbit IgG (whole molecule)-FITC antibody produced in goat has been used in immunohistochemistry and indirect immunofluorescence.

Actions biochimiques/physiologiques

Immunoglobulin G (IgG) provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. IgG1 deficiency results in hypogammaglobulinemia. IgG2 deficiency increases susceptibility to bacterial infections IgG3 mediates effector functions IgG4 are associated with asymptomatic infection. IgG antibody have enormous therapeutic potential and the Fc region is involved for the development of therapeutic antibody.

Autres remarques

Antibody adsorbed with human IgG.

Forme physique

Solution in 0.01 M phosphate buffered saline, pH 7.4, with 15 mM sodium azide as a preservative.

Notes préparatoires

Adsorbed to reduce background staining with human samples.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Opposite regulation of tenascin-C and tenascin-X in MeLiM swine heritable cutaneous malignant melanoma
Geffrotin C, et al.
Biochim. Biophys. Acta Gen. Subj., 1524(2-3), 196-202 (2000)
Francisco J Sancho-Bielsa et al.
PloS one, 7(11), e48470-e48470 (2012-11-13)
The molecular layer of the dentate gyrus appears as the main entrance gate for information into the hippocampus, i.e., where the perforant path axons from the entorhinal cortex synapse onto the spines and dendrites of granule cells. A few dispersed
Tirtha K Datta et al.
Reproduction (Cambridge, England), 149(2), 203-212 (2014-11-12)
Upstream stimulating factor 1 (USF1) is a basic helix-loop-helix transcription factor that specifically binds to E-box DNA motifs, known cis-elements of key oocyte expressed genes essential for oocyte and early embryonic development. However, the functional and regulatory role of USF1
Co-localization of inducible nitric oxide synthase and phosphorylated Akt in the lesional skins of patients with melasma
JO HY, et al.
The Journal of dermatology, 36(1), 10-16 (2009)
Joseph A Waldron et al.
Biology open, 4(5), 649-660 (2015-04-04)
Programmed cell death, or apoptosis, is a highly conserved cellular process that is crucial for tissue homeostasis under normal development as well as environmental stress. Misregulation of apoptosis is linked to many developmental defects and diseases such as tumour formation
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