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D5764

Sigma-Aldrich

2,3-Diphospho-D-glyceric acid pentasodium salt

glycolysis metabolite

Synonyme(s) :

2,3-DPG, D-Glycerate 2,3-diphosphate sodium salt

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About This Item

Formule linéaire :
C3H3O10P2Na5
Numéro CAS:
102783-53-9
Poids moléculaire :
375.95
Numéro MDL:
MFCD00070074
Code UNSPSC :
12352201
ID de substance PubChem :
24893967
Nomenclature NACRES :
NA.25

Source biologique

synthetic

Niveau de qualité

200

Forme

powder

Impuretés

3-phosphoglyceric acid, essentially free

Couleur

white to off-white

Solubilité

water: 100 mg/mL, clear, colorless to faintly yellow

Traces de cations

Na: 24.5-32.5% (anhydrous)

Température de stockage

−20°C

Chaîne SMILES 

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

Clé InChI

JJEMSNINYKJOBZ-YBBRRFGFSA-N

Application

D-Glycerate 2,3-diphosphate, cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites.

Actions biochimiques/physiologiques

Metabolite of glycolysis within human erythrocytes produced by 2,3-diphosphoglycerate mutase in an alternative to the glycolytic pathway. Binds to hemaglobin to reduce oxygenation.

Autres remarques

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Minke A E Rab et al.
American journal of hematology, 94(5), 575-584 (2019-02-21)
In sickle cell disease (SCD), sickle hemoglobin (HbS) polymerizes upon deoxygenation, resulting in sickling of red blood cells (RBCs). These sickled RBCs have strongly reduced deformability, leading to vaso-occlusive crises and chronic hemolytic anemia. To date, there are no reliable
Chiara Crestani et al.
Journal of veterinary internal medicine, 32(3), 1051-1059 (2018-04-11)
Optimal procedure for storage of feline blood is needed. Open-collection systems have been employed in feline medicine, thus limiting the possibility for storage. To evaluate indicators of quality of feline blood stored for 35 days at +4°C in a closed-collection
Manon Bardyn et al.
Metabolites, 10(6) (2020-06-04)
After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurrence of storage lesions. In this study
H Gulliksson et al.
Vox sanguinis, 112(1), 33-39 (2016-12-22)
The present general plasticizer di-2-ethylhexyl-phthalate in polyvinylchloride (PVC) blood bags is only physically dispersed in PVC and will therefore leach into blood components. The objective of this study was to perform a first preliminary red blood cell (RBC) storage evaluation
Sitong Zhou et al.
Science advances, 5(5), eaaw4466-eaaw4466 (2019-06-01)
The tight coupling between cerebral blood flow and neural activity is a key feature of normal brain function and forms the basis of functional hyperemia. The mechanisms coupling neural activity to vascular responses, however, remain elusive despite decades of research.
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