C9538

Coenzyme Q₁₀

≥98% (HPLC), powder, antioxidant

• Synonyme(s) : CoQ10, Q-10, Ubiquinone 50, Ubiquinone-10
• Formule empirique (notation de Hill): C₅₉H₉₀O₄
• Numéro CAS: 303-98-0
• Poids moléculaire : 863.34
• Numéro Beilstein : 1900141
• Numéro CE : 206-147-9
• Numéro MDL: MFCD00042919
• Code UNSPSC : 12352200
• ID de substance PubChem : 24893170
• Nomenclature NACRES : NA.77

Propriétés

• product name: Coenzyme Q₁₀, ≥98% (HPLC)
• Niveau de qualité: 200
• Pureté: ≥98% (HPLC)
• Forme: powder
• Couleur: yellow to dark orange
• Pf: 49 °C
• Application(s): cell analysis
• Température de stockage: −20°C
• Chaîne SMILES: O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O
• InChI: 1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+
• Clé InChI: ACTIUHUUMQJHFO-UPTCCGCDSA-N

Description

Description générale

Coenzyme Q (CoQ), also known as ubiquinone, is a lipid-soluble antioxidant and is an essential component of the mitochondrial electron transport chain. The molecule contains a biologically active quinone with a benzoquinone ring and an isoprenoid sidechain. Q10 is synthesized in the cytoplasm and mitochondria () which generates ATP through aerobic cellular respiration. CoQ10 is required for the optimal functioning of the immune system and for cardiovascular health (). The ability to repress inflammatory gene expression exhibits its anti-inflammatory property ( ) Genetic failure or ageing results in CoQ10 deficiency, indicated by suppression of immune function. ()

Application

Coenzyme Q10 (CoQ10) has been used:

• as a bioactive compound to study its immune modulating properties in vitro
• as a standard for high-performance liquid chromatography
• to study its effect on exercised rat aorta
• in the cellular CoQ uptake assay

Actions biochimiques/physiologiques

Coenzyme Q10 is an endogenous cellular antioxidant and an essential component of the electron transfer chain. CoQ10 takes part in aerobic cellular respiration and generation of energy in the form of ATP.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)