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C6445

Sigma-Aldrich

Cholate de sodium hydrate

BioXtra, ≥99%

Synonyme(s) :

Acide 3α,7α,12α-trihydroxy-5β-cholan-24-oïque sodium salt, Acide cholalique sodium salt

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About This Item

Formule empirique (notation de Hill):
C24H39NaO5 · xH2O
Numéro CAS:
206986-87-0
Poids moléculaire :
430.55 (anhydrous basis)
Numéro Beilstein :
3582354
Numéro CE :
206-643-5
Numéro MDL:
MFCD00150749
Code UNSPSC :
12161900
ID de substance PubChem :
24892867
Nomenclature NACRES :
NA.25

Description

anionic

Niveau de qualité

200

Gamme de produits

BioXtra

Pureté

≥99%

Forme

powder

Poids mol.

micellar avg mol wt 900-1300

Nombre d'agrégation

2-3

Impuretés

≤0.05% Phosphorus (P)
≤0.1% Insoluble matter

CMC

9-15 mM (20-25°C)

Solubilité

H2O: 1 M, clear, faintly yellow to yellow

Traces d'anions

sulfate (SO42-): ≤0.05%

Traces de cations

Al: ≤0.005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

HLB

18

Chaîne SMILES 

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1

Clé InChI

MUVVIYFKOVLQHL-RCVKHMDESA-M

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Catégories apparentées

Description générale

Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins.

Application

Sodium cholate hydrate has been used in a study to assess infiltration of pressurized promoter solutions in a mesoporous silica.
Sodium cholate hydrate has been used:
  • as a component of biofilm growth media along with tryptic soy broth (TSB) to test the effects of each bile salt on biofilm formation
  • as a detergent to study its effect on cannabinoid receptor 1 (CB1) detection by western blot
  • as a promoter to prepare solution B for the synthesis of tungsten disulfide (WS2) on a SiO2/Si wafer

Caractéristiques et avantages

  • pH range 5-8
  • Suitable for membrane technology and culture media

Mentions de danger

H412

Conseils de prudence

P273 - P501

Classification des risques

Aquatic Chronic 3

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Fang Fang et al.
Journal of bacteriology, 191(18), 5743-5757 (2009-07-14)
Commensal lactobacilli frequently produce bile salt hydrolase (Bsh) enzymes whose roles in intestinal survival are unclear. Twenty-six Lactobacillus salivarius strains from different sources all harbored a bsh1 allele on their respective megaplasmids. This allele was related to the plasmid-borne bsh1
Infiltration of pressurized promoter solutions in a mesoporous silica
Punyamurtula and Qiao
Microporous Mater., 103, 5-5 (2007)
Mavis Jiarong Li et al.
Current protocols in protein science, 98(1), e100-e100 (2019-11-21)
Lipid nanodiscs provide a native-like lipid environment for membrane proteins, and they have become a valuable platform for the study of membrane biophysics. A range of biophysical and biochemical analyses are enabled when membrane proteins are captured in lipid nanodiscs.
Thuc Hue Ly et al.
Nature communications, 7, 10426-10426 (2016-01-28)
Grain boundaries in monolayer transition metal dichalcogenides have unique atomic defect structures and band dispersion relations that depend on the inter-domain misorientation angle. Here, we explore misorientation angle-dependent electrical transport at grain boundaries in monolayer MoS2 by correlating the atomic
Volkan K Köseoğlu et al.
Infection and immunity, 87(7) (2019-04-17)
Shigella flexneri is an intracellular bacterial pathogen that invades epithelial cells in the colonic mucosa, leading to bloody diarrhea. A previous study showed that S. flexneri forms biofilms in the presence of bile salts, through an unknown mechanism. Here, we
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