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C1629

Sigma-Aldrich

Choline bitartrate

Synonyme(s) :

2-(Hydroxyethyl)trimethylammonium bitartrate

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About This Item

Formule empirique (notation de Hill):
C9H19NO7
Numéro CAS:
87-67-2
Poids moléculaire :
253.25
Numéro CE :
201-763-4
Code UNSPSC :
12352200
ID de substance PubChem :
24892428
Nomenclature NACRES :
NA.77

Forme

powder

Niveau de qualité

200

Chaîne SMILES 

[O-]C([C@H](O)[C@@H](O)C(O)=O)=O.C[N+](C)(C)CCO

InChI

1S/C5H14NO.C4H6O6/c1-6(2,3)4-5-7;5-1(3(7)8)2(6)4(9)10/h7H,4-5H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/q+1;/p-1/t;1-,2-/m.1/s1

Clé InChI

QWJSAWXRUVVRLH-LREBCSMRSA-M

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Application

Choline bitartrate has been used as one of the components in experimental diets to study the effects on reproductive processes and on bone genes during gestation and lactation.

Actions biochimiques/physiologiques

Choline bitartrate is known to serve as a dietary supplement. Choline acts as a precursor for acetylcholine synthesis.
Acyl group acceptor

Substrats

Choline acetyltransferase substrate

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

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Chlorure de choline

SAFC

PHG0021

Chlorure de choline

Chlorure de choline BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98%

Sigma-Aldrich

C7527

Chlorure de choline

tert-Butylhydroquinone 97%

Sigma-Aldrich

112941

tert-Butylhydroquinone

Lard oil

Sigma-Aldrich

L0657

Lard oil

Yumna Zia et al.
The Journal of nutrition, 148(10), 1513-1520 (2018-10-04)
Phosphatidylethanolamine N-methyltransferase (PEMT) converts phosphatidylethanolamine to phosphatidylcholine. Pemt-/-/low density lipoprotein receptor (Ldlr)-/- mice have significantly reduced plasma lipids and are protected against atherosclerosis. Recent studies have shown that choline can be metabolized by the gut flora into trimethylamine-N-oxide (TMAO), which
O T Pantako et al.
Reproduction, nutrition, development, 41(3), 227-238 (2001-10-11)
The effects of two dietary proteins on alpha-amino acids, calcium and phosphorus concentrations in plasma, stomach and intestine were investigated in rats trained to consume, in a single two-hour daily meal, diets containing a-lactalbumin (alpha-la) or whey protein concentrate (WPC)
Jacob H Murray et al.
Journal of medicinal chemistry, 66(6), 3876-3895 (2023-03-08)
Small-molecule mitochondrial uncouplers are gaining recognition as potential therapeutics for metabolic diseases such as obesity, diabetes, and nonalcoholic steatohepatitis (NASH). Specifically, heterocycles derived from BAM15, a potent and mitochondria-selective uncoupler, have yielded promising preclinical candidates that are efficacious in animal
Extra virgin olive oil in maternal diet increases osteogenic genes expression, but high amounts have deleterious effects on bones in mice offspring at adolescence
Mousavi SN, et al.
Iranian Journal of Basic Medical Sciences, 19(12), 1299-1299 (2016)
Siamak Sheikhi et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 84(2), 109-121 (2024-02-05)
The mother's thyroid hormone status during gestation and the first few months after delivery can play a crucial role in maturation during the brain development of the child. Transient abnormalities in thyroid function at birth indicate developmental and cognitive disorders
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