375810

Periodic acid

ACS reagent, 99%

• Formule empirique (notation de Hill): H₅IO₆
• Numéro CAS: 10450-60-9
• Poids moléculaire : 227.94
• Numéro CE : 233-937-0
• Numéro MDL: MFCD00011344
• Code UNSPSC : 12352106
• ID de substance PubChem : 329755660
• Nomenclature NACRES : NA.21

Propriétés

• Qualité: ACS reagent
• Niveau de qualité: 200
• Pureté: 99%; 99.0-101.0% (ACS specification)
• Forme: powder or crystals
• Capacité de réaction: reaction type: C-H Activation
• Pertinence de la réaction: reagent type: catalyst; reagent type: oxidant
• Impuretés: ≤0.01% insolubles; ≤0.01% other halogens
• Résidus de calcination: ≤0.01%
• Pf: 122 °C (lit.)
• Solubilité: water: soluble
• Traces d'anions: sulfate (SO₄^2-): ≤0.01%
• Traces de cations: Fe: ≤0.003%; heavy metals: ≤0.005%
• Application(s): histology
• Chaîne SMILES: OI(O)(O)(O)(O)=O
• InChI: 1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)
• Clé InChI: TWLXDPFBEPBAQB-UHFFFAOYSA-N

Description

Description générale

Periodic acid is an inorganic acid commonly used as an oxidizing agent. Periodic acid oxidation is one of the steps in the periodate-resorcinol assay, used in the determination of sialic acid. Periodic acid reacts with 1,2 glycol linkage of carbohydrates to form aldehydes which can be stained by Schiff′s reagent. Therefore periodic-acid-Schiff′s reagent (PAS) is used in histochemistry to determine carbohydrates in tissue sections.

Application

Periodic acid may be used in the following reactions:

• Oxidation of alcohols to ketones and aldehydes.
• Oxidation hydroxylamine derivatives.
• Oxidation of arenes to quinones.
• Deprotection of the dithio- and oxathio-derivatives.
• Oxidative degradation of epoxidized natural rubber (ENR).
• Oxidation of urazoles and bis-urazoles to triazolinediones.
• Oxidative cleavage of glucosazone.

Informations sur la sécurité

• Pictogrammes: GHS03,GHS08,GHS05,GHS09
• Mention d'avertissement: Danger
• Mentions de danger: H271,H314,H372,H410
• Conseils de prudence: P210 - P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Classification des risques: Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1B - STOT RE 1 Oral
• Organes cibles: Thyroid
• Code de la classe de stockage: 5.1A - Strongly oxidizing hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable