PHR1075
Cimetidine
Pharmaceutical Secondary Standard; Certified Reference Material
Synonyme(s) :
SKF-92334
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About This Item
Formule empirique (notation de Hill):
C10H16N6S
Numéro CAS:
Poids moléculaire :
252.34
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24
Produits recommandés
Qualité
certified reference material
pharmaceutical secondary standard
Niveau de qualité
Agence
traceable to BP 475
traceable to Ph. Eur. C2175000
traceable to USP 1134062
Famille d'API
cimetidine
CofA (certificat d'analyse)
current certificate can be downloaded
Technique(s)
HPLC: suitable
gas chromatography (GC): suitable
Application(s)
pharmaceutical (small molecule)
Format
neat
Température de stockage
2-8°C
Chaîne SMILES
CN\C(NC#N)=N\CCSCc1nc[nH]c1C
InChI
1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
Clé InChI
AQIXAKUUQRKLND-UHFFFAOYSA-N
Informations sur le gène
human ... HRH2(3274)
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Description générale
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cimetidine is an H2 receptor antagonist drug. It can inhibit the photosensitive response on the skin typically induced by most of the fluoroquinolones.
Cimetidine is an H2 receptor antagonist drug. It can inhibit the photosensitive response on the skin typically induced by most of the fluoroquinolones.
Application
Cimetidine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Remarque sur l'analyse
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Autres remarques
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Note de bas de page
To see an example of a Certificate of Analysis for this material enter LRAA7170 in the slot below. This is an example certificate only and may not be the lot that you receive.
Produits recommandés
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Produit(s) apparenté(s)
Réf. du produit
Description
Tarif
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
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Les clients ont également consulté
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Quimica nova, 34(4), 683-688 (2011)
Determination of cimetidine, famotidine, and ranitidine hydrochloride in the presence of their sulfoxide derivatives in pure and dosage forms by high-performance thin-layer chromatography and scanning densitometry
Kelani KM, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 85(5), 1015-1020 (2002)
A Kumar
DICP : the annals of pharmacotherapy, 24(3), 289-295 (1990-03-01)
Suppressor T lymphocytes possess histamine2 (H2) receptors and contribute significantly to the function of the immune system. Experimentally, cimetidine, an H2-receptor antagonist, has been shown to enhance a variety of immunologic functions both in vivo and in vitro because of
P San Miguel et al.
Virchows Archiv : an international journal of pathology, 430(3), 261-263 (1997-03-01)
A case of carcinoma in the breast of a male patient with a chronic gastric ulcer is described. The patient had received cimetidine for 17 years. Histological examination of an excisional biopsy showed lobular in situ and infiltrating carcinoma. In
A F Shinn
Drug safety, 7(4), 245-267 (1992-07-01)
The excellent efficacy and tolerability profiles of H2-antagonists have established these agents as the leading class of antiulcer drugs. Attention has been focused on drug interactions with H2-antagonists as a means of product differentiation and because many patients are receiving
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