Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

PHR1214

Supelco

Methyl salicylate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Essence de gaulthéria, Ester méthylique d’acide 2-hydroxybenzoïque

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme


About This Item

Formule linéaire :
2-(HO)C6H4CO2CH3
Numéro CAS:
Poids moléculaire :
152.15
Numéro Beilstein :
971516
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to USP 1537450

Densité de vapeur

5.26 (vs air)

Pression de vapeur

1 mmHg ( 54 °C)

Famille d'API

methyl salicylate

CofA (certificat d'analyse)

current certificate can be downloaded

Température d'inflammation spontanée

847 °F

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Indice de réfraction

n20/D 1.536 (lit.)

Point d'ébullition

222 °C (lit.)

Pf

−8-−7 °C (lit.)

Densité

1.174 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

COC(=O)c1ccccc1O

InChI

1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3

Clé InChI

OSWPMRLSEDHDFF-UHFFFAOYSA-N

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Methyl salicylate is one of the common ingredients present in topical analgesics and rubifacients. It is prescribed for the management of minor muscle aches and pains.

Application

Methyl salicylate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and voltammetry techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC3556 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogrammes

Health hazardCorrosionExclamation mark

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1B

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

204.8 °F - closed cup

Point d'éclair (°C)

96 °C - closed cup


Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Optimization and validation of liquid chromatography and headspace-gas chromatography based methods for the quantitative determination of capsaicinoids, salicylic acid, glycol monosalicylate, methyl salicylate, ethyl salicylate, camphor and l-menthol in a topical formulation
Pauwels J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 60(3), 51-58 (2012)
Determination of salicylic acid in pharmaceutical formulations and foods by differential-pulse voltammetry using a glassy carbon electrode
Fung YS and Luk SF
Analyst, 114(8), 943-945 (1989)
Fourier transform mid-infrared (MIR) and near-infrared (NIR) spectroscopy for rapid quality assessment of Chinese medicine preparation Honghua Oil
Wu YW, et al.
Journal of Pharmaceutical and Biomedical Analysis, 46(3), 498-504 (2008)
Agata Bartyzel et al.
Analytica chimica acta, 707(1-2), 204-209 (2011-10-27)
N,N'-bis-(α-methylsalicylidene)-2,2-dimethyl-1,3-propanediimine (SBTD) modified silica gel was prepared and used as sorbent for solid phase extraction of Cr(III) ions from aqueous solution. This sorbent showed a high sorption affinity for Cr(III) while recovery of Cr(VI) was very low. The analyte ion
J S Valdez et al.
Journal of chromatography. B, Biomedical sciences and applications, 729(1-2), 163-171 (1999-07-20)
Analytical methods using gas chromatography-flame ionization detection (GC-FID) for the quantitation of camphor and menthol and GC-MS for the quantitation of methyl salicylate have been developed for measurement of low concentrations from human plasma. Anethole serves as the internal standard

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique