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Key Documents

D6001

Sigma-Aldrich

Sulfate de dextran sodium salt from Leuconostoc spp.

average mol wt >500,000 (dextran starting material), contains 0.5-2.0% phosphate buffer, pH 6-8

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.21

Source biologique

bacterial (Leuconostoc mesenteroides)

Niveau de qualité

Forme

powder

Activité optique

[α]/D 90 to 105 °, c = 6% (w/v) in water

Poids mol.

average mol wt >500,000 (dextran starting material)

Contient

0.5-2.0% phosphate buffer, pH 6-8

Composition

Sulfur Content, 16.0-19.0%

Couleur

white to off-white

Plage de pH utile

6.0-8.0 (1% in water)

Solubilité

H2O: 100 mg/mL

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Description générale

Dextran sulfate is a negatively charged sulfated polysaccharide, which is produced by the esterification of dextran with chlorosulphonic acid. It has antiviral, anticoagulant and adjuvant properties. Dextran is used to treat hemorrhage, burns, surgery and trauma. It enhances blood flow and blocks erythrocyte aggregation. Dextran decreases the risk of thrombosis and postoperative pulmonary emboli. It acts as a ribonuclease inhibitor.

Application

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • to delipidate fatty plasma(67)(70)
  • to induce inflammatory and carcinogenic response in the distal colon of rodents(68)
  • for the preparation of 3,4-ethylenedioxythiophene (EDOT)(69)

Autres remarques

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

The Molecular Biology of Poliovirus (2012)
Seda Onder et al.
Frontiers in pharmacology, 8, 713-713 (2017-10-27)
Hupresin is a new affinity resin that binds butyrylcholinesterase (BChE) in human plasma and acetylcholinesterase (AChE) solubilized from red blood cells (RBC). Hupresin is available from the CHEMFORASE company. BChE in human plasma binds to Hupresin and is released with
Zora Djuric et al.
The Journal of nutritional biochemistry, 46, 90-99 (2017-05-10)
Dietary fish oils have potential for prevention of colon cancer, and yet the mechanisms of action in normal and tumor colon tissues are not well defined. Here we evaluated the impact of the colonic fatty acid milieu on the formation
The Molecular Biology of Poliovirus (2012)
Delipidation of plasma has minimal effects on human butyrylcholinesterase
Onder S, et al.
Frontiers in Pharmacology, 9, 117-117 (2018)

Protocoles

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Contenu apparenté

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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