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Key Documents

D4911

Sigma-Aldrich

Sulfate de dextran sodium salt from Leuconostoc spp.

mol wt 6,500-10,000

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.21

Source biologique

bacterial (Leuconostoc)

Niveau de qualité

Forme

powder

Poids mol.

6,500-10,000

Composition

Sulfur Content, 16.0-22.0%

Couleur

white to light yellow

Plage de pH utile

6.0-8 (10 g/L)

Solubilité

H2O: 100 mg/mL

Température de stockage

room temp

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Description générale

Dextran sulfate is a sulfated polysaccharide, which is negatively charged. It is produced by the esterification of dextran with chlorosulphonic acid. Dextran is used to treat hemorrhage, burns, surgery and trauma. It improves blood flow and prevents erythrocyte aggregation. Dextran lowers the risk of thrombosis and postoperative pulmonary emboli. It is a ribonuclease inhibitor. Dextran sulfate exhibits antiviral, anticoagulant and adjuvant properties.

Application

Dextran sulfate sodium salt Leuconostoc spp has been used:
  • as a standard to perform polyacrylamide-gel electrophoresis for carbohydrates (C-PAGE)(59) and agarose gel electrophoresis(60)
  • for RNA sequential probing of targets (SPOTs) imaging(61)
  • as a component of 1% injection buffer(62)

Autres remarques

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Radiotherapy, Surgery, and Immunotherapy (2012)
Parisa Yousefpour et al.
International journal of nanomedicine, 6, 1487-1496 (2011-07-29)
This study deals with the preparation and investigation of a nanoscale delivery system for the anticancer drug doxorubicin (DOX) using its complexation with polyanionic carbohydrate dextran sulfate (DS). Dynamic light scattering, SEM, and zeta potential determination were used to characterize
Rheology of Industrial Polysaccharides: Theory and Applications (2012)
Valter R M Lombardi et al.
Journal of biomedicine & biotechnology, 2012, 826178-826178 (2012-05-24)
One of the main treatments currently used in humans to fight cancer is chemotherapy. A huge number of compounds with antitumor activity are present in nature, and many of their derivatives are produced by microorganisms. However, the search for new
The Molecular Biology of Poliovirus (2012)

Protocoles

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Dextran sulfates as sodium salts are water-soluble and stable, containing approximately 17% sulfur for various applications.

Contenu apparenté

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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