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D4784

Sigma-Aldrich

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride

≥98% purity (HPLC), powder

Synonyme(s) :

1,2-Diamino-4,5-methylenedioxybenzene dihydrochloride, 1,3-Benzodioxole-5,6-diamine dihydrochloride, 5,6-Diamino-1,3-benzodioxole dihydrochloride, MDB

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About This Item

Formule empirique (notation de Hill):
C7H8N2O2 · 2HCl
Numéro CAS:
81864-15-5
Poids moléculaire :
225.07
Numéro Beilstein :
5641607
Numéro MDL:
MFCD00037497
Code UNSPSC :
12171500
ID de substance PubChem :
24893897
Nomenclature NACRES :
NA.47

product name

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride, Fluorogenic reagent

Niveau de qualité

100

Pureté

≥98% (HPLC)

Forme

powder

Technique(s)

titration: suitable

Couleur

white to orange

Pf

247 °C

Solubilité

H2O: 50 mg/mL

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

−20°C

Chaîne SMILES 

Cl[H].Cl[H].Nc1cc2OCOc2cc1N

InChI

1S/C7H8N2O2.2ClH/c8-4-1-6-7(2-5(4)9)11-3-10-6;;/h1-2H,3,8-9H2;2*1H

Clé InChI

YXEJRYIEFFUUID-UHFFFAOYSA-N

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Catégories apparentées

Description générale

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride is a fluorescence tag for α keto acids. It is also required for the derivatization of sialic acids in presence of dilute sulfuric acid. The method allows determination of sialic acids.

Application

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride has been used for the derivatization of sialic acids to analyse them by capillary liquid-chromatography-electrospray ionization/tandem mass spectrometry (CapLC-ESI-MS/MS).
Fluorogenic reagent for α-ketoacids.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319,H335

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
MKCV7881
MKCT5835
MKCS5232
MKCR7321
MKCM9235

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Capillary Electrophoresis of Carbohydrates (2010)
Savaş İzzetoğlu et al.
Fish & shellfish immunology, 36(1), 181-186 (2013-11-13)
Coelomocytes are considered to be immune effectors of sea urchins. Coelomocytes are the freely circulating cells in the body fluid contained in echinoderm coelom and mediate the cellular defence responses to immune challenges by phagocytosis, encapsulation, cytotoxicity and the production
Determination of sialic acids in immune system cells (coelomocytes) of sea urchin, Paracentrotus lividus, using capillary LC-ESI-MS/MS.
Izzetoglu S, et al.
Fish & Shellfish Immunology, 36, 181-186 (2014)
Determination of the type and quantity of sialic acid in the egg jelly coat of the sea urchin Paracentrotus lividus using capillary LC-ESI-MS/MS.
Yesilyurt B, et al.
Molecular Reproduction and Development, 82, 115-122 (2015)
Xiaoxiao Guo et al.
The Analyst, 145(13), 4512-4521 (2020-05-16)
The polysialyltransferases (polySTs) catalyse the polymerisation of polysialic acid, which plays an important role in tumour metastasis. While assays are available to assess polyST enzyme activity, there is no methodology available specifically optimised for identification and quantitative evaluation of potential
Afficher tous les articles scientifiques apparentés

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A significantly improved HPLC-fluorescence method for DMB-NANA and -NGNA, and application of this method to compare 2 candidate biosimilar therapeutic proteins to their respective RMs.

Improving the Chromatographic Separation of DMB-Labeled Sialic Acids for the Comparison of Biosimilars to Reference Materials

A significantly improved HPLC-fluorescence method for DMB-NANA and -NGNA, and application of this method to compare 2 candidate biosimilar therapeutic proteins to their respective RMs.

Improving the Chromatographic Separation of DMB-Labeled Sialic Acids for the Comparison of Biosimilars to Reference Materials

A significantly improved HPLC-fluorescence method for DMB-NANA and -NGNA, and application of this method to compare 2 candidate biosimilar therapeutic proteins to their respective RMs.

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