A4673

Albendazole

analytical standard, ≥98%

• Synonyme(s) : Methyl 5-(propylthio)-2-benzimidazolecarbamate
• Formule empirique (notation de Hill): C₁₂H₁₅N₃O₂S
• Numéro CAS: 54965-21-8
• Poids moléculaire : 265.33
• Numéro CE : 259-414-7
• Numéro MDL: MFCD00083232
• Code UNSPSC : 41116107
• ID de substance PubChem : 329770859
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Pureté: ≥98%
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): forensics and toxicology; pharmaceutical (small molecule)
• Format: neat
• Chaîne SMILES: CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1
• InChI: 1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
• Clé InChI: HXHWSAZORRCQMX-UHFFFAOYSA-N

Description

Description générale

Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite.

Chemical structure: benzimidazole

Application

Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Binds to tubulin and inhibits microtubule assembly.

Informations sur la sécurité

• Pictogrammes: GHS08,GHS09
• Mention d'avertissement: Warning
• Mentions de danger: H361d,H373,H410
• Conseils de prudence: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Classification des risques: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Oral
• Organes cibles: Adrenal gland,Blood,male reproductive organs,spleen
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)