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Cannabidiolic acid

analytical standard

Synonyme(s) :

CBDA

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About This Item

Formule empirique (notation de Hill):
C22H30O4
Numéro CAS:
1244-58-2
Poids moléculaire :
358.47
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Pureté

≥95% (HPLC)

Durée de conservation

limited shelf life, expiry date on the label

Contrôle du médicament

USDEA Schedule I; Home Office Schedule 1; regulated under CDSA - not available from Sigma-Aldrich Canada

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable
solid phase extraction (SPE): suitable

Adéquation

in accordance for H-NMR

Application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Température de stockage

−20°C

Chaîne SMILES 

CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1C(O)=O

InChI

1S/C22H30O4/c1-5-6-7-8-15-12-18(23)20(21(24)19(15)22(25)26)17-11-14(4)9-10-16(17)13(2)3/h11-12,16-17,23-24H,2,5-10H2,1,3-4H3,(H,25,26)/t16-,17+/m0/s1

Clé InChI

WVOLTBSCXRRQFR-DLBZAZTESA-N

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Catégories apparentées

Description générale

Cannabidiolic acid belongs to the group of cannabinoids, a class of psychoactive and non-psychoactive compounds produced in the Cannabis (marijuana) plant. It is an acidic precursor,(4) which shows potential therapeutic efficacy in the treatment of pain, mood disorders, and inflammatory diseases.

Application

Cannabidiolic acid has been used as an analytical standard for the quantification of the analyte in biomass, extracts of different varieties of cannabis, and commercial cannabis products using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H361d

Classification des risques

Acute Tox. 4 Oral - Repr. 2

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
BCCM1260
BCCL7480
BCCH7605
BCCG0971
BCCF3880

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Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

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Shuso Takeda et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(9), 1917-1921 (2008-06-17)
In the present study it was revealed that cannabidiolic acid (CBDA) selectively inhibited cyclooxygenase (COX)-2 activity with an IC(50) value (50% inhibition concentration) around 2 microM, having 9-fold higher selectivity than COX-1 inhibition. In contrast, Delta(9)-tetrahydrocannabinolic acid (Delta(9)-THCA) was a
Commercial cannabis consumer products part 2: HPLC-DAD quantitative analysis of cannabis cannabinoids
Ciolino aL, et al.
Forensic Science International, 289(6), 438-447 (2018)
Elizabeth M Mudge et al.
Analytical and bioanalytical chemistry, 409(12), 3153-3163 (2017-02-25)
There is an explosion in the number of labs analyzing cannabinoids in marijuana (Cannabis sativa L., Cannabaceae) but existing methods are inefficient, require expert analysts, and use large volumes of potentially environmentally damaging solvents. The objective of this work was
D Bolognini et al.
British journal of pharmacology, 168(6), 1456-1470 (2012-11-06)
To evaluate the ability of cannabidiolic acid (CBDA) to reduce nausea and vomiting and enhance 5-HT(1A) receptor activation in animal models. We investigated the effect of CBDA on (i) lithium chloride (LiCl)-induced conditioned gaping to a flavour (nausea-induced behaviour) or
Roger G Pertwee et al.
British journal of pharmacology, 175(1), 100-112 (2017-10-24)
The aim of this study was to compare the abilities of cannabidiolic acid methyl ester (HU-580) and cannabidiolic acid (CBDA) to enhance 5-HT We investigated the effects of HU-580 and CBDA on (i) activation by 8-hydroxy-2-(di-n-propylamino)tetralin of human 5-HT HU-580
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