37022

(−)-Scopolamine hydrochloride

analytical standard

• Synonyme(s) : Hyoscine hydrochloride, Scopine tropate
• Formule empirique (notation de Hill): C₁₇H₂₁NO₄ · HCl
• Numéro CAS: 55-16-3
• Poids moléculaire : 339.81
• Numéro Beilstein : 4168778
• Numéro CE : 200-225-6
• Numéro MDL: MFCD00058096
• Code UNSPSC : 85151701
• ID de substance PubChem : 329755587
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: analytical standard
• Niveau de qualité: 100
• Durée de conservation: limited shelf life, expiry date on the label
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Application(s): cleaning products; cosmetics; food and beverages; personal care
• Format: neat
• Température de stockage: −20°C
• Chaîne SMILES: Cl.[H][C@]12C[C@H](C[C@]([H])(N1C)[C@]3([H])O[C@]23[H])OC(=O)[C@H](CO)c4ccccc4
• InChI: 1S/C17H21NO4.ClH/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;1H/t11-,12-,13-,14+,15-,16+;/m1./s1
• Clé InChI: KXPXJGYSEPEXMF-MOUKNHLCSA-N
• Informations sur le gène: human ... CHRM1(1128)

Description

Description générale

(−)-Scopolamine hydrochloride belongs to the class of naturally occurring tropane alkaloids of medicinal interest, found in several members of the Solanaceae family, commonly Atropa belladonna and representatives of the genera Datura and Duboisia.

For the analysis of the phytotoxins.

Application

(−)-Scopolamine hydrochloride may be used as a precursor for the preparation of scopolamine, employed as an analytical standard for the quantification of the scopolamine in the floral nectar and plant organs of Datura species using various chromatographic techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Actions biochimiques/physiologiques

Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit.

Reconstitution

Dried down, concentration of (S)-(-)-Scopolamine (free base) after reconstitution ~100μg/mL

Remarque sur l'analyse

purity : ≥96.0% (HPLC)

Informations sur la sécurité

• Pictogrammes: GHS06,GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H300 + H310 + H330,H317,H318
• Conseils de prudence: P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
• Classification des risques: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Sens. 1
• Code de la classe de stockage: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable