Accéder au contenu
Merck
Toutes les photos(1)

Key Documents

34124

Supelco

Deoxynivalenol solution

100 μg/mL in acetonitrile, analytical standard

Synonyme(s) :

3α,7α,15-Trihydroxy-12,13-epoxytrichothec-9-en-8-one, DON, Vomitoxin

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme


About This Item

Formule empirique (notation de Hill):
C15H20O6
Numéro CAS:
Poids moléculaire :
296.32
Numéro CE :
Numéro MDL:
Code UNSPSC :
85151701
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Durée de conservation

limited shelf life, expiry date on the label

Concentration

100 μg/mL in acetonitrile

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

cleaning products
cosmetics
food and beverages
personal care

Format

single component solution

Température de stockage

−20°C

Chaîne SMILES 

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O

InChI

1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1

Clé InChI

LINOMUASTDIRTM-QGRHZQQGSA-N

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Description générale

Deoxynivalenol belongs to the group of tetracyclic sesquiterpenoid mycotoxins called trichothecenes, produced by Fusarium fungi, naturally occurring in small grains and infected corn.

Check out our entire range of trichothecene type mycotoxin reference materials
Deoxynivalenol is frequently found in cereals and agricultural products including, corn, barley, oats, rye, maize, wheat, malt, bread, beer, etc. It is a mycotoxin and primarily affects the livestock industry by reducing the food intake in farm animals. The effect of DON contamination in cereals and other food samples serves as one of the factors of Kashin-Beck disease, a chronic and endemic osteoarticular disorder.

Application

Deoxynivalenol solution has been used as an analytical reference standard for the quantification of the analyte in cornmeal and wheat meal matrices using high-performance liquid chromatography with UV detection (HPLC-UV). It is used as an analytical standard in investigating its toxicity mechanism on human chondrocytes by microarray and bioinformatics analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictogrammes

FlameExclamation mark

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

35.6 °F - closed cup

Point d'éclair (°C)

2 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

Vous ne trouvez pas la bonne version ?

Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Determination of 12 type A and B trichothecenes in cereals by liquid chromatography? electrospray ionization tandem mass spectrometry
Klotzel M, et al.
Journal of Agricultural and Food Chemistry, 53, 8904-8910 (2005)
Production of monoclonal antibodies for the specific detection of deoxynivalenol and 15-acetyldeoxynivalenol by ELISA
Sinha.CR, et al.
Journal of Agricultural and Food Chemistry, 43, 1740-1744 (1995)
Lei Yang et al.
Toxicology letters, 321, 61-68 (2019-12-22)
T-2 toxin and deoxynivalenol (DON) are two representative mycotoxins that are commonly found in cereals and agricultural products. As T-2 toxin and DON are considered the cause of Kashin-Beck disease, a special osteoarticular disease, chondrocytes would be a vital target
Giuseppina Avantaggiato et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(5), 817-824 (2004-03-30)
In vitro screening of 14 adsorbent materials, including some commercial products used to detoxify Fusarium-mycotoxins, were tested in the pH range of 3-8 for deoxynivalenol (DON)- and nivalenol (NIV)-binding ability. Only activated carbon showed to be effective with binding capacities
Michihiro Ito et al.
Applied and environmental microbiology, 79(5), 1619-1628 (2013-01-01)
Deoxynivalenol (DON) is a natural toxin of fungi that cause Fusarium head blight disease of wheat and other small-grain cereals. DON accumulates in infected grains and promotes the spread of the infection on wheat, posing serious problems to grain production.

Contenu apparenté

Detailed list of mycotoxin analysis products for Food & Beverage manufacturers and testers, ensuring safety standards.

Detailed list of mycotoxin analysis products for Food & Beverage manufacturers and testers, ensuring safety standards.

Detailed list of mycotoxin analysis products for Food & Beverage manufacturers and testers, ensuring safety standards.

Detailed list of mycotoxin analysis products for Food & Beverage manufacturers and testers, ensuring safety standards.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique