211842

Brilliant Black BN

Dye content 60 %

• Synonyme(s) : Food Black 1
• Formule empirique (notation de Hill): C₂₈H₁₇N₅Na₄O₁₄S₄
• Numéro CAS: 2519-30-4
• Poids moléculaire : 867.68
• Numéro C.I. (Colour Index): 28440
• Numéro CE : 219-746-5
• Numéro MDL: MFCD00078980
• Code UNSPSC : 12171500
• ID de substance PubChem : 24852710
• Nomenclature NACRES : NA.47

Propriétés

• Forme: powder
• Niveau de qualité: 200
• Composition: Dye content, 60%
• λmax: 407 nm (2nd); 570 nm
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: [Na+].[Na+].[Na+].[Na+].CC(=O)Nc1ccc(c2cc(c(\N=N\c3ccc(\N=N/c4ccc(cc4)S([O-])(=O)=O)c5ccc(cc35)S([O-])(=O)=O)c(O)c12)S([O-])(=O)=O)S([O-])(=O)=O
• InChI: 1S/C28H21N5O14S4.4Na/c1-14(34)29-23-10-11-24(50(42,43)44)20-13-25(51(45,46)47)27(28(35)26(20)23)33-32-22-9-8-21(18-7-6-17(12-19(18)22)49(39,40)41)31-30-15-2-4-16(5-3-15)48(36,37)38;;;;/h2-13,35H,1H3,(H,29,34)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47);;;;/q;4*+1/p-4/b31-30-,33-32+;;;;
• Clé InChI: GMMAPXRGRVJYJY-OXYXOBGMSA-J

Description

Application

Brilliant Black BN has been used:

• in micronucleus and comet assays to evaluate its genotoxic effect.
• as a quenching agent in calcium mobilization assay.
• as a redox indicator in microbiological inhibition bioassay using Bacillus megaterium to detect tetracycline and macrolides in milk.

Actions biochimiques/physiologiques

[4-acetamido-5-hydroxy-6-[7-sulfonato-4-(4-sulfonatophenylazo)-1-naphtylazo], also known as food black 1, belongs to the group of azo dyes. Brilliant Black BN is widely used as a food dye and pharmaceutical excipient. In addition, it also acts as an allosteric modulator of the adenosine A1 and A3 receptors and is generally used within calcium mobilization assays to reduce extracellular fluorescence.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)