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Key Documents

MAB5504

Sigma-Aldrich

Anti-Vesicular Glutamate Transporter 2 Antibody

clone 8G9.2, Chemicon®, from mouse

Synonyme(s) :

VGLUT2

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

100

Forme d'anticorps

purified antibody

Type de produit anticorps

primary antibodies

Clone

8G9.2, monoclonal

Espèces réactives

mouse, rat

Réactivité de l'espèce (prédite par homologie)

human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Isotype

IgG1

Numéro d'accès NCBI

NM_020346.1

Numéro d'accès UniProt

Q9JI12

Conditions d'expédition

wet ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... SLC17A6(57084)

Description générale

Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity.

Spécificité

Reacts with VGLUT2 (Vesicular Glutamate Transporter 2).

Application

Detect Vesicular Glutamate Transporter 2 using this Anti-Vesicular Glutamate Transporter 2 Antibody validated for use in WB, IH.
Immunohistochemistry: A 1:50-1:300 dilution of a previous lot worked using ABC with NiDAB on floating mouse brain sections.

Optimal working dilutions must be determined by end user.

Qualité

Evaluated by Western Blot on Mouse brain lysates.

Western Blotting Analysis: 1:500 dilution of this antibody detected VGLUT2 on 10 µg of Mouse brain lysates.

Description de la cible

56 kDa

Forme physique

Format: Purified
Mouse monoclonal in PBS containing 0.1% sodium azide.

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Tarif

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 2

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

I Pose et al.
Neuroscience, 172, 246-255 (2010-11-04)
The rostral ventro-medial medullary reticular formation is a complex structure that is involved with a variety of motor functions. It contains glycinergic neurons that are activated during active (rapid eye movement (REM)) sleep (AS); these neurons appear to be responsible
Purkinje cell ataxin-1 modulates climbing fiber synaptic input in developing and adult mouse cerebellum.
Ebner, BA; Ingram, MA; Barnes, JA; Duvick, LA; Frisch, JL; Clark, HB; Zoghbi, HY; Ebner, TJ; Orr, HT
The Journal of Neuroscience null
Peiyan Wong et al.
The Journal of comparative neurology, 510(4), 440-461 (2008-07-31)
The temporal cortex of grey squirrels contains three architectonically distinct regions. One of these regions, the temporal anterior (Ta) region has been identified in previous physiological and anatomical studies as containing several areas that are largely auditory in function. Consistent
SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.
Duvick, L; Barnes, J; Ebner, B; Agrawal, S; Andresen, M; Lim, J; Giesler, GJ; Zoghbi, HY; Orr, HT
Neuron null
Chia-Chi Liao et al.
The Journal of comparative neurology, 524(7), 1494-1526 (2015-11-01)
A complete unilateral lesion of the dorsal column somatosensory pathway in the upper cervical spinal cord deactivates neurons in the hand region in contralateral somatosensory cortex (areas 3b and 1). Over weeks to months of recovery, parts of the hand
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