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Merck
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Principaux documents

AG208

Sigma-Aldrich

VGT 1 Peptide

control for AB5905, liquid

Synonyme(s) :

VGLUT1, BNPI

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.42

product name

Vesicular Glutamate Transporter 1, control peptide for AB5905,

Source biologique

rat

Niveau de qualité

Forme

liquid

Fabricant/nom de marque

Chemicon®

Concentration

1 mg/mL

Technique(s)

cell based assay: suitable

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Description générale

Synthetic peptide from rat VGLUT1 protein.
VGLUT1 is expressed in a subset of glutamate neurons and transports glutamate into native synaptic vesicles from the brain, exhibiting a conductance for chloride that is blocked by glutamate. Vesicular glutamate transport has a substantially lower apparent affinity than the plasma membrane excitatory amino acid transporters. Glutamate transport by VGLUT1 is saturated with a K(m) of approximately 2 mM, in the same range as transport by synaptic vesicles. Finally, plasma membrane glutamate transporters recognize both aspartate and glutamate as substrates, whereas VGLUT1 does not recognize aspartate.

Application

For use in blocking the reactivity of AB5905.

Optimal working dilution must be determined by the end user.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Sean P Masterson et al.
The Journal of comparative neurology, 515(6), 647-663 (2009-06-06)
Dorsal thalamic nuclei have been categorized as either "first-order" nuclei that gate the transfer of relatively unaltered signals from the periphery to the cortex or "higher order" nuclei that transfer signals from one cortical area to another. To classify the
Seth L Shipman et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(47), 19432-19437 (2012-11-07)
The transsynaptic complex of neuroligin (NLGN) and neurexin forms a physical connection between pre- and postsynaptic neurons that occurs early in the course of new synapse assembly. Both neuroligin and neurexin have, indeed, been proposed to exhibit active, instructive roles
Synaptotagmins I and II in the developing rat auditory brainstem: Synaptotagmin I is transiently expressed in glutamate-releasing immature inhibitory terminals.
Alan P Cooper,Deda C Gillespie
The Journal of Comparative Neurology null
Alain C Burette et al.
The Journal of comparative neurology, 520(7), 1481-1492 (2011-11-22)
The sodium-driven chloride/bicarbonate exchanger (NDCBE), a member of the SLC4 family of bicarbonate transporters, was recently found to modulate excitatory neurotransmission in hippocampus. By using light and electron microscopic immunohistochemistry, we demonstrate here that NDCBE is expressed throughout the adult
VGLUT1 and VGLUT2 innervation in autonomic regions of intact and transected rat spinal cord.
Ida J Llewellyn-Smith,Carolyn L Martin,Natalie M Fenwick,Stephen E Dicarlo,Heidi L Lujan et al.
The Journal of Comparative Neurology null

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