8.20925

2-Octanol

for synthesis

• Synonyme(s) : 2-Octanol, Hexyl methyl carbinol, 2-Capryl alcohol
• Formule linéaire : CH₃(CH₂)₅CH(OH)CH₃
• Numéro CAS: 123-96-6
• Poids moléculaire : 130.23
• Numéro MDL: MFCD00004591
• Code UNSPSC : 12352104
• Numéro de classement CE : 204-667-0
• Nomenclature NACRES : NA.22

Propriétés

• Pression de vapeur: 0.25 hPa ( 20 °C)
• Niveau de qualité: 200
• Pureté: ≥98% (GC)
• Forme: oil
• Température d'inflammation spontanée: 255-260 °C
• Puissance: 6100 mg/kg LD₅₀, oral (Rat)
• Limite d'explosivité: 0.80-7.40 % (v/v)
• Point d'ébullition: 177-182 °C/1013 hPa
• Pf: -38 °C
• Température de transition: flash point 71 °C
• Densité: 0.82 g/cm³ at 20 °C
• Température de stockage: 2-30°C
• InChI: 1S/C8H18O/c1-3-4-5-6-7-8(2)9/h8-9H,3-7H2,1-2H3
• Clé InChI: SJWFXCIHNDVPSH-UHFFFAOYSA-N

Description

Application

• Development of a mixed solvent system for the efficient resolution of (R, S)-2-octanol catalyzed by magnetite-immobilized lipase: This study presents a novel solvent system enhancing the enantioselectivity and activity of lipase in the resolution of 2-octanol, a key intermediate in synthesizing chiral building blocks used in drug development (Liu et al., 2014).
• Efficient Kinetic Resolution of (R,S)-2-Octanol Catalyzed by Magnetite-Immobilized Yarrowia lipolytica Lipase in Mixed Ionic Liquids: This research explores using ionic liquids with immobilized lipase for resolving 2-Octanol, crucial for producing enantiopure substances in pharmacological synthesis (Liu et al., 2014).
• Effect of hydrazyl radical on the selectivity of γ-alumina with different sizes of pores for dehydration of 2-octanol through radical elimination mechanism: Investigates the interaction between hydrazyl radicals and 2-octanol on γ-alumina, relevant for understanding catalytic mechanisms in material science (Alidoust et al., 2023).
• Process hazard evaluation for catalytic oxidation of 2-octanol with hydrogen peroxide using calorimetry techniques: Assesses the safety and kinetic parameters of 2-octanol oxidation, important for chemical process design in industrial and academic settings (Sun et al., 2019).
• Enhancing the resolution of (R, S)-2-octanol catalyzed by magnetic cross-linked lipase aggregates using an alternating magnetic field: Describes a method to improve the enantioselective resolution of 2-Octanol using magnetic fields, potentially useful for scaling up chiral resolutions in pharmaceutical manufacturing (Liu et al., 2015).

Remarque sur l'analyse

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.820 - 0.822
Identity (IR): passes test

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H318
• Conseils de prudence: P280 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1
• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 159.8 °F - closed cup
• Point d'éclair (°C): 71 °C - closed cup